Results 81 to 90 of about 96,711 (304)

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Ferrocene-derived magnetic fiber-particles from diesel exhaust: enhanced pulmonary toxicity via Bach1-SAT1-polyamine depletion

Journal of Nanobiotechnology
Background and aim Magnetic nanoparticles are key components of air pollution. The combustion of diesel engine fuels, especially with ferrocene doping to reduce emissions, may increase exposure to these particles and related health risks.
Xinxian Gong, Siyi Wang, Junhua Yuan, Jing Ji, Rui Zhao, Jing Huang, Boyang Li, Yunuo Zhai, Yuxu Zhong, Yuxin Zheng, Qixiao Jiang   +10 more
doaj   +1 more source

A case report of juvenile Huntington disease

Journal of Pediatric and Neonatal Individualized Medicine, 2017
Huntington disease (HD) is a progressive neurodegenerative disorder, characterized by autosomal dominant inheritance, movement disorder, dementia, and behavioural disturbances.
Anita Choudhary, Priyanka Minocha, Sadasivan Sitaraman   +2 more
doaj   +1 more source

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming

Advanced Materials, EarlyView.
Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung, Emie Humann, Joshua M. Price, Yoav Binenbaum, Azra Haseki, Sanjana Iyer, David J. Mooney   +6 more
wiley   +1 more source

Fabric‐Based Wearable Robotic Exoskeleton Gloves: Advancements and Challenges

Advanced Materials Technologies, EarlyView.
This review highlights interdisciplinary technological advances in fabric‐based robotic gloves, focusing on progress in design, fabrication, actuation, sensing, control, and power and energy requirements. It also addresses performance testing and validation, including biomechanical, strength, functional, user experience, and durability assessments, to ...
Ayse Feyza Yilmaz, Gökhan Ince, Ozgur Atalay   +2 more
wiley   +1 more source

YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation [PDF]

, 2019
Yes-associated protein (YAP) is a transcriptional co-factor involved in many cell processes, including development, proliferation, stemness, differentiation, and tumorigenesis.
Amicone, Laura, Battistelli, Cecilia, Cicchini, Carla, Consalvi, Veronica, Cozzolino, Angela Maria, Marchetti, Alessandra, Noce, Valeria, Strippoli, Raffaele, Tripodi, Marco   +8 more
core   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

APC-β-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis. [PDF]

, 2020
Sporadic colorectal cancer initiates with mutations in APC or its degradation target β-catenin, producing TCF-dependent nuclear transcription driving tumorigenesis. The intestinal epithelial receptor, GUCY2C, with its canonical paracrine hormone guanylin,
Bashir, Babar, Blomain, Erik S, Caparosa, Ellen, Pattison, Amanda M, Rappaport, Jeffrey A, Snook, Adam E, Stem, Jonathan, Waldman, Scott A   +7 more
core   +1 more source

Analogy electromagnetism-acoustics: Validation and application to local impedance active control for sound absorption [PDF]

, 1998
An analogy between electromagnetism and acoustics is presented in 2D. The propagation of sound in presence of absorbing material is modeled using an open boundary microwave package.
Furstoss, M., Galland, Marie-Annick, Nicolas, Laurent   +2 more
core   +3 more sources

Molecular Appendix Adjusted Architectural Propagations of Red‐Light Controlled Macroscopic Photoactuating Performances

Advanced Robotics Research, EarlyView.
Amphiphilic chloroazobenzenes, bearing different amino acids as end groups alanine, phenylalanine, and valine, exhibit excellent photoisomerizations. Varying structures of three amino acid groups participate in supramolecular formations and therefore photoinduced morphological transformations via adjusting intermolecular interactions. These interaction
Shuangshuang Meng, Ming‐Hin Chau, Takashi Kajitani, Franco King‐Chi Leung   +3 more
wiley   +1 more source