Results 81 to 90 of about 276,181 (347)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Influence of Magnetic Field on Atrazine Adsorption and Degradation by Ferroxite and Hematite

Magnetism
This study approaches the characterization of Ferroxite and Hematite and the test of their magnetic properties on the degradation and adsorption of Atrazine, an herbicide of the triazine class.
Marcos Antônio Sousa, Mateus Aquino Gonçalves, Thais Aparecida Sales, Jessica Boreli dos Reis Lino, Stéfany Gonçalves de Moura, Joaquim Paulo da Silva, Teodorico Castro Ramalho   +6 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Magnetic Field Analysis of Unconventional High Surge Impedance Loading (HSIL) Transmission Lines with Different Subconductor Configurations: Numerical Comparisons and Performance Evaluation

Magnetism
High-voltage transmission lines are the backbone of modern power systems, facilitating the delivery of electricity from diverse generation sources, including conventional power plants and renewable energy systems, to consumers.
Easir Arafat, Babak Porkar, Mona Ghassemi   +2 more
doaj   +1 more source

Muon Spin Relaxation Studies of Magnetic-Field-Induced Effects in High-$T_{c}$ Superconductors

, 2005
Muon spin relaxation ($\mu$SR) measurements in high transverse magnetic fields ($\parallel \hat c$) revealed strong field-induced quasi-static magnetism in the underdoped and Eu doped (La,Sr)$_{2}$CuO$_{4}$ and La$_{1.875}$Ba$_{0.125}$CuO$_{4}$, existing
Eisaki, H., Fukaya, A., Gat-Malureanu, I. M., Goto, M., Greven, M., Gu, G. D., Ito, T., Kadono, R., Kaneko, N., Kojima, K. M., Kyriakou, P. P., Luke, G. M., MacDougall, G. J., Masui, T., Rovers, M. T., Russo, P. L., Savici, A. T., Tajima, S., Uchida, S., Uemura, Y. J., Wiebe, C. R., Yamada, K.   +21 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Effect of the Non-Magnetic Ion Doping on the Magnetic Behavior of MgCr₂O₄

Magnetism
Geometrically frustrated magnets exhibit exotic excitations due to competing interactions between spins. The spinel compound MgCr2O4, a three-dimensional Heisenberg antiferromagnet, hosts both spin-wave and spin-resonance modes, but the origin of its ...
Fuxi Zhou, Zheng He, Donger Cheng, Han Ge, Wenjing Zhang, Xiao Wang, Pengfei Zhou, Wanju Luo, Zhengdong Fu, Xinzhi Liu, Liusuo Wu, Lunhua He, Yanchun Zhao, Erxi Feng   +13 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Interpretation of Magnetism and Gravitation as Relational Residual Effects of the Electric Force

Magnetism
This article demonstrates that magnetic force and Newton’s law of universal gravitation can be derived from the solution of Maxwell’s equations for moving point charges. For this purpose, a plasma droplet model is postulated, consisting of an aggregation
Steffen Kühn
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source