Results 91 to 100 of about 236,983 (297)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
KEK effort for high field magnets
, 2011 KEK has emphasized efforts to develop the RHQNb3Al superconductor and a sub-scale magnet reaching 13 T towards the HL-LHC upgrade in last years. In addition, relevant R&D regarding radiation resistance has been carried out.
Nakamoto, T.
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Investigations on the performances of the electrical generator of a rim-driven marine current turbine” [PDF]
, 2014 In this paper, the electrical generator of a rim-driven horizontal-axis current turbine is modeled in detail. Its main characteristics and performances are evaluated (efficiency, mass, cost, etc).
CHARPENTIER, Jean-Frederic +3 more
core +1 more source
Continuous Versus First Order Transitions in Compressible Diluted Magnets
, 1996 The interplay between disorder and compressibility in Ising magnets is studied. Contrary to pure systems in which a weak compressibility drives the transition first order, we find from a renormalization group analysis that it has no effect on disordered ...
Aharony +30 more
core +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Materials & DesignNd-Fe-B magnets with 30 at.% Y substitution were prepared using single-main-phase (SMP) and multi-main-phase (MMP) techniques to investigate the differences in magnetic properties and microstructures between spontaneously formed core–shell structures in ...
Sining Fan +11 more
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Effect of Annealing, Stoichiometry, and Surface on Magnetism of (Pr,Dy)FeCoB Microparticles Ensemble
Archives of Metallurgy and Materials, 2017 Magnetic properties of powder (Pr,Dy)FeCoB ferrimagnetic alloys and effects of annealing, surface states were analyzed. X-ray photoelectron spectroscopy and Mössbauer spectra of powders indicate the effect of surface states on phase composition and ...
Kablov E.N. +5 more
doaj +1 more source