Results 121 to 130 of about 2,455,254 (309)

Hearing loss among children with sickle cell disease at a tertiary hospital in Tanzania

open access: yesJournal of the Colleges of Medicine of South Africa
Background: Sickle cell disease (SCD) is documented to cause sensorineural hearing loss. Although no major international guideline formally mandates routine audiological screening for all patients with SCD, multiple studies and meta-analyses have ...
Innocent Kimaro   +5 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Prevalence and associated factors of self-medication among pregnant women in Sodo Town, Southern Ethiopia

open access: yesFrontiers in Medicine
BackgroundSelf-medication is a widespread practice among pregnant women worldwide, with 44.55% practicing it. However, it may lead to incorrect diagnosis, inappropriate treatment, and failure to recognize contraindications.
Mesfin Abebe   +5 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Reassessing the Location, Magnitude, and Macroseismic Intensity Map of the 8 April 1893 Svilajnac (Serbia) Earthquake

open access: yesApplied Sciences
A devastating earthquake took place on 8 April 1893, close to the town of Svilajnac, central Serbia. Over the past decade, significant historical data on the effects of this earthquake has been collected from a variety of sources, including books ...
Miodrag I. Manić, Borko Đ. Bulajić
doaj   +1 more source

Government Banking in Russia: Magnitude and New Features [PDF]

open access: yes
State-controlled banks are currently at the core of financial intermediation in Russia. This paper aims to assess the magnitude of government banking, and to reveal some of its special features and arrangements.
Andrei Vernikov
core  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Long-Term Correlations in São Francisco River Flow: The Influence of Sobradinho Dam

open access: yesRevista Brasileira de Meteorologia
In this work we study the influence of the Sobradinho dam construction on daily streamflow of São Francisco River, Brasil, by analyzing long-range correlations in magnitude and sign time series obtained from streamflow anomalies, using the Detrended ...
Ikaro Daniel de Carvalho Barreto   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

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