Results 41 to 50 of about 23,223 (259)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

How long can you store vitamins? Stability of tocopherols and tocotrienol during different storage conditions in broccoli and blueberries

Food Chemistry: X
Differences between the stability of α-, β-, γ-, and δ-tocopherol as well α-tocotrienol stored at −20 °C and −80 °C were studied in broccoli and blueberry samples.
Irmela Sarvan, Anton Jürgensen, Matthias Greiner, Oliver Lindtner   +3 more
doaj   +1 more source

Surface Modification of Silica Nanoparticles with Ethyl Oleate for the Purpose of Stabilizing Nanolubricants Used for Tribological Tests

Ceramics, 2023
Long-term sustainability and decreasing amount of fossil oil reserves require a partial or complete transformation of traditional lubricating oils. The use of silica nanoparticles as a lubricant additive has a huge tribological potential, which has ...
Álmos Dávid Tóth, Nóra Mike-Kaszás, Gábor Bartus, Hajnalka Hargitai, Ádám István Szabó   +4 more
doaj   +1 more source

An updated and refined catalog of earthquakes in Taiwan (1900–2014) with homogenized M w magnitudes [PDF]

Earth, Planets and Space, 2016
The main goal of this study was to develop an updated and refined catalog of earthquakes in Taiwan (1900–2014) with homogenized M w magnitudes that are compatible with the Harvard M w .
Chang, Wen-Yen, Chen, Kuei-Pao, Tsai, Yi- Ben   +2 more
openaire   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Empirical relations between magnitudes mb/Ms, Ms/Mw and mb/Mc in the area of Cuba, Jamaica and Hispaniola

Minería y Geología, 2018
Empirical relationships among different magnitude scales reported by regional sources and the Cuban Seismological Service for earthquakes in the area of Cuba, Jamaica and Hispaniola Islands are calculated for catalog homogenization purposes.
Madelín Villalón-Semanat, Raúl Palau-Clares   +1 more
doaj  

Economic tolerance design of the P2 raceway based on the quasi-static model of aerospace ball bearings

Scientific Reports
This study focused on designing the raceway tolerance of high-precision rolling bearings. After the tolerance error equivalence relationship is defined, the application of the rolling bearing error equalization effect in tolerance design is studied ...
Zhou Chang, Lai Hu, Wenhan Cao
doaj   +1 more source

Phase Transformations in Rapidly Solidified Al-Cu-Li-Mg-Sc-Zr Alloy During Model Homogenization Studied by In Situ STEM

Crystals
Rapid solidification by melt-spinning produces aluminum alloys with extremely refined microstructures but also introduces strong structural gradients across the ribbon thickness.
Rostislav Králík, Barbora Kihoulou, Lucia Bajtošová, Tomáš Krajňák, Miroslav Cieslar   +4 more
doaj   +1 more source