Results 141 to 150 of about 15,385,090 (308)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Controlling és alkalmazása az egészségügyben
, 2009 A controlling-rendszerről elmondható, hogy - a hagyományos számviteli felfogással ellentétben - nem alkalmaz teljes költségfelosztást, és az intézményben zajló gazdasági folyamatokat nem éves vagy féléves csúszással követi, hanem az adott időszak ...
Takács, Péter
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Presentation of controlling system at Tranzit-Ker Zrt.
, 2019 Diplomadolgozatomban a Tranzit-Ker Zrt. controlling rendszerét fogom bemutatni. Mivel egy jól felépített controlling rendszer sok szempontból fontos egy vállalkozás életében, érdekelt hogyan is működik ez egy évek óta eredményesen működő cégnél.
Fekete, Petra
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Az Erste Bank Hungary Zrt. elemzése controlling szempontból
, 2013 Diplomamunkám középpontjában a hitelintézet, valamint a működésének sikerességét megalapozó egyik alrendszere, a controlling rendszer áll. A controlling rendszer szerepe minden vállalkozás, így a hitelintézetek működésében is megkérdőjelezhetetlen. Ez az
Lőrincz, Andrea
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
, 2011 WO3 microcrystallites:One of the crucial factors controlling the isomerization activity of Pt/WO3 ...
JuanjuanZhang +5 more
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source