Results 101 to 110 of about 166,212 (332)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

MIDST: an enhanced development environment that improves the maintainability of a data science analysis

open access: yesInternational Journal of Information Systems and Project Management, 2021
With the increasing ability to generate actionable insight from data, the field of data science has seen significant growth. As more teams develop data science solutions, the analytical code they develop will need to be enhanced in the future, by an ...
Jeffrey S. Saltz   +3 more
doaj  

On the Analysis of a Wave Energy Farm with Focus on Maintenance Operations

open access: yesJournal of Marine Science and Engineering, 2016
Wave energy has a promising technical potential that could contribute to the future energy mix. However, costs related to the deployment of wave energy converters (WECs) are still high compared to other technologies.
Giovanni Rinaldi   +3 more
doaj   +1 more source

To maintain or not, that is the question [PDF]

open access: yesBritish Journal of Haematology, 2015
Paw Jensen   +4 more
openaire   +3 more sources

Maintaining surgical professionalism [PDF]

open access: yesThe Annals of The Royal College of Surgeons of England, 2011
The Royal College of Physicians working party on medical professionalism defined it as 'a set of values, behaviours and relationships that underpins the trust the public has in doctors.' In essence professionalism incorporates competence, consistency, autonomy, honesty and integrity. It should be reflected in actions, work, speech, dress and behaviour.
openaire   +4 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Object-oriented Tools for Distributed Computing [PDF]

open access: yes, 1993
Distributed computing systems are proliferating, owing to the availability of powerful, affordable microcomputers and inexpensive communication networks.
Adler, Richard M.
core   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Aquarium Setup and Maintainence

open access: yesEDIS, 1969
An aquarium can be defined as a container that holds water and is designed in such a way that living aquatic organisms can be maintained over an extended period of time. Aquariums vary tremendously in size and design. They can be as simple as a betta bowl or as complex as a multi-million gallon commercial exhibit.
Roy P. E. Yanong   +2 more
openaire   +5 more sources

ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function

open access: yesFEBS Letters, EarlyView.
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran   +6 more
wiley   +1 more source

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