On some Experiments in which Two Neighbouring maintained Oscillatory Circuits affect a Resonating Circuit [PDF]
, 1919 James H. Vincent
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Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
Maintainability Assessment during the Design Phase: Integrating MTA and UNE 151001
MachinesThe focus on maintenance actions in the early design phases has been a trend in recent years. The main sources of information during the design of the maintainability process include operator reports, maintainer experience, failure history, and ...
Franco Donaire +3 more
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The CROONIAN LECTURES on the MEANS by which the TEMPERATURE of the BODY is MAINTAINED in HEALTH and DISEASE: Delivered before the Royal College of Physicians of London [PDF]
, 1897 W. H. White
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A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
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Maintaining perioperative normothermia
BMJ, 2003 Perioperative hypothermia can have a wide range of underappreciated, detrimental effects. These include increased rates of wound infection, morbid cardiac events, blood loss, and length of stay in both recovery and hospital. Maintaining core temperature at or above 36°C can be beneficial for the patient and cost effective.
Shan Gowrie-Mohan +2 more
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FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
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The Influence of 1:2:5:6-Dibenzanthracene on the Nucleic Acid Content of the Liver of Rats Maintained on High and Low Protein Diets [PDF]
, 1947 L. A. Elson, R. J. C. Harris
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Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
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