Results 71 to 80 of about 13,846 (260)

PERSPECTIVES OF THE METHODS DEVELOPMENT FOR AIRCRAFT MAINTAINABILITY CERTIFICATION

open access: yesНаучный вестник МГТУ ГА, 2018
The paper outlines the main problems and perspectives of methods development for regulation and finding compliance of aircraft during the type design maintainability certification. Mentioned requirements and methods relevance are related to the fact that
Yu. A. Yaloza, A. N. Petrov
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Maintaining Quality

open access: yesSurvey Research Methods, 2015
Survey Research Methods, Vol 9, No 3 (2015)
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A STUDY OF QUALITY IN THE PROCESS OF SOFTWARE PRODUCT DEVELOPMENT ACCORDING TO MAINTAINABILITY AND REUSABILITY [PDF]

open access: yes
Our research indicates the modality by which algorithm modifications imply intervention in modules where expressions are evaluated or selections of elements are performed, the conclusion being the fact that in order to design robust software, a clear ...
Andy STEFĂNESCU   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Measuring Software Maintainability: An Exploration of Metrics and Continuous Practices

open access: yes
Maintainability is a critical aspect of modern software projects, referring to the ease with which a system can be modified, repaired, or adapted to changing requirements.
Syed-Mohamad, Sharifah Mashita   +3 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

RAM analysis of earth pressure balance tunnel boring machines: A case study [PDF]

open access: yesInternational Journal of Mining and Geo-Engineering, 2015
Earth pressure balance tunnel boring machines (EPB-TBMs) are favorably applied in urban tunneling projects. Despite their numerous advantages, considerable delays and high maintenance cost are the main disadvantages these machines suffer from ...
Hasel Amini Khoshalan   +3 more
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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