Results 21 to 30 of about 6,138,855 (383)

Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma.

open access: yesNew England Journal of Medicine, 2020
BACKGROUND Platinum-based chemotherapy is standard-of-care first-line treatment for advanced urothelial carcinoma. However, progression-free survival and overall survival are limited by chemotherapy resistance.
T. Powles   +26 more
semanticscholar   +1 more source

Structure Formation and Properties of Concrete Based on Organic Hydraulic Binders

open access: yesНаука и техника, 2020
The article addresses the issues of structure formation of road composite materials containing hydraulic (рortland cement) and organic (bitumen) binders. It has been determined that organic and hydraulic binders, being thermodynamically incompatible, are
B. M. Khroustalev   +6 more
doaj   +1 more source

Study on the Deformation of Pavement Structure with Multiplex Organic Hydraulicity Mixture under Driving Load Based on Simulation and Experiment

open access: yesAdvances in Materials Science and Engineering, 2021
With the continuous growth of global warming and traffic volume, rutting deformation is common on road surfaces. A new type of pavement mixture, a semiflexible mixture, was proposed to solve the easy deformation and low riding quality of traditional ...
Hairong Gu   +5 more
doaj   +1 more source

Date Palm Fiber-Reinforced Recycled Polymer Composites: Synthesis and Characterization

open access: yesAdvances in Polymer Technology, 2022
In this research study, Recycled Polymer (RP) composites are synthesized by using compression molding process, initial mixtures of RP and Date Palm Fibers (DPF) with four different lengths (e.g., 2.5, 5, 7.5, and 10 mm) and weight ratios (e.g., 5, 10, 15,
Malek Ali   +2 more
doaj   +1 more source

Evaluation of the Refined Decomposition Effect of Reclaimed Asphalt Pavement Materials

open access: yesBuildings, 2023
To improve the quality of reclaimed asphalt pavement materials (RAPs) and reduce the variability of RAPs, a refined decomposition process was applied to treat RAPs.
Peng Wang   +7 more
doaj   +1 more source

Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer.

open access: yesNew England Journal of Medicine, 2019
BACKGROUND Olaparib has shown significant clinical benefit as maintenance therapy in women with newly diagnosed advanced ovarian cancer with a BRCA mutation.
I. Ray-Coquard   +29 more
semanticscholar   +1 more source

LARP7 family proteins have conserved function in telomerase assembly

open access: yesNature Communications, 2018
The telomerase holoenzyme is minimally composed of the reverse transcriptase and the RNA template. Here the authors identify Lar7 as a member of the full complex that helps to stabilise it and protect telomerase RNA from degradation.
Laura C. Collopy   +11 more
doaj   +1 more source

Evaluation of Measurement Strategy for Track Side Monitoring of Railway Wheels

open access: yesApplied Sciences, 2023
Wheelsets form an indispensable part of the railway rolling stock and need to be periodically inspected to ensure stable, safe, reliable, and sustainable rail operation.
Matti Rantatalo   +6 more
doaj   +1 more source

Infliximab for induction and maintenance therapy for ulcerative colitis.

open access: yesNew England Journal of Medicine, 2005
BACKGROUND Infliximab, a chimeric monoclonal antibody directed against tumor necrosis factor alpha, is an established treatment for Crohn's disease but not ulcerative colitis. METHODS Two randomized, double-blind, placebo-controlled studies--the Active
P. Rutgeerts   +13 more
semanticscholar   +1 more source

Predictive Maintenance and Intelligent Sensors in Smart Factory: Review

open access: yesItalian National Conference on Sensors, 2021
With the arrival of new technologies in modern smart factories, automated predictive maintenance is also related to production robotisation. Intelligent sensors make it possible to obtain an ever-increasing amount of data, which must be analysed ...
Martin Pech, J. Vrchota, Jiří Bednář
semanticscholar   +1 more source

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