Results 101 to 110 of about 310,072 (254)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Unleashing the Power of Very Small Data to Predict Acute Exacerbations of Chronic Obstructive Pulmonary Disease

open access: yesInternational Journal of COPD, 2023
Petra Kristina Jacobson,1,2 Leili Lind,3,4 Hans Lennart Persson1,2 1Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; 2Department of Respiratory Medicine in Linköping, Linköping University, Linköping, Sweden ...
Jacobson PK, Lind L, Persson HL
doaj  

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Systematic Review of Automated Diuresis Measurement in Critically Ill Patients

open access: yesMedical Devices: Evidence and Research, 2023
Jose-Luis Lafuente,1,2,* Samuel González,1,3 Vicente Gómez-Tello,1,4 Enrique Puertas,1,5 Eva Avilés,1,2 Juan-Jose Beunza1,6,* 1IASalud, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid, Spain; 2Department of Engineering, Universidad ...
Lafuente JL   +5 more
doaj  

Successful Cessation Programs that Reduce Comorbidity May Explain Surprisingly Low Smoking Rates Among Hospitalized COVID-19 Patients [PDF]

open access: yes, 2020
A recent, non-peer-reviewed meta-analysis suggests that smoking may reduce the risk of hospitalization with COVID-19 because the prevalence of smoking among hospitalized COVID-19 is less than that of the general population.
Alvarez, R. Michael   +7 more
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Engineered Exosome for Drug Delivery: Recent Development and Clinical Applications

open access: yesInternational Journal of Nanomedicine, 2023
Jiaqi Tian,1,* Zhengpu Han,1,2,* Dandan Song,1 Yanjie Peng,1 Min Xiong,3 Zhen Chen,2 Shuyin Duan,4 Lin Zhang1,5 1Clinical Medical Research Center for Women and Children Diseases, Shandong Provincial Maternal and Child Health Care Hospital ...
Tian J   +7 more
doaj  

North Slope Borough water study: a background for planning [PDF]

open access: yes, 1977
The Planning and Research Section of Alaska Dept. of Natural Resources initiated this pilot water study with the North Slope Borough and the University of Alaska's Arctic Environmental Information and Data Center and Institute of Water Resources ...
Dreyer, Linda Dwight, Johnson, Ronald A.
core  

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

216 Jewish Hospital of St. Louis [PDF]

open access: yes, 1953
https://digitalcommons.wustl.edu/bjc_216/1014/thumbnail ...

core   +1 more source

Home - About - Disclaimer - Privacy