Results 41 to 50 of about 71,800 (241)

Geometric design and mechanical performance of isotropic bone scaffolds

Materials & Design
Bone tissue engineering scaffolds with reduced elastic anisotropy, enhanced mechanical performance, and high ratio of surface to volume are continuous pursuits.
Rongwei Xu, Zhou Zhang, Zhen Peng, Fuyuan Deng, Zhong Li, Xu Liu, Liang He   +6 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Measurement device and derivation formula for static ocular compliance

Scientific Reports
To introduce a device for measuring static ocular compliance (SOC) and propose a best-fit formula. An observational experimental study involving patients with age-related cataracts was conducted between May 2024 and September 2024.
Suchang Wang, Shancheng Si, Wenwen Hou, Ming Zhang, Guimin Zhang   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Hypervolemia screening in predialysis healthcare for hemodialysis patients using fuzzy color reason analysis

International Journal of Distributed Sensor Networks, 2017
Maintaining adequate dry weight and fluid volume balance is an important issue for dialysis patients. Malnutrition and sodium intake are the primary factors that cause fluid volume imbalance and changes in body weights.
Wei-Ling Chen, Chung-Dann Kan, Chia-Hung Lin, Ying-Shin Chen, Yi-Chen Mai   +4 more
doaj   +1 more source

Investigating a cluster of pediatric oncology invasive fungal infections–Lessons learned

Antimicrobial Stewardship & Healthcare Epidemiology, 2022
Background: In spring 2021, the infection prevention and control department at a pediatric academic medical center identified 3 oncology patients with concern for invasive Rhizopus spp infections.
Angelette Terk, Jennifer Ormsby, Paula Conrad, Catherine Svensson, David Barry, David Davis, Ana Vaughan Malloy, Tom Sandora   +7 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

From neglect to necessity: a community case study on the strategic recovery of 57 ventilators during the COVID-19 pandemic

Frontiers in Health Services
BackgroundThe COVID-19 pandemic precipitated a critical global shortage of mechanical ventilators, life-saving devices essential for managing patients with severe respiratory complications.
Meshari Rashed Albuqami, Ghadah Sulaiman Alsaleh, Ghadah Sulaiman Alsaleh, Ibrahim Saud Altrair, Marie Hamed Alqahtani, Fahad Mansour Alanazi, Mohmmed Fahad Alqahtani, Faisal Hawas Alattawi, Abdulaziz Abdullah Alshehri, Abdulrahman Bakhat Alzahrani, Abdulrahman Ayed Alruwaili, Reem Abdulrahman Alshehri, Ali Mohmmed Alshehri, Sarah Hassan Alqahtani   +13 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Hardware/engineering battery-operated drills are more cost-effective as compared to orthopedic drills

Journal of Orthopaedic Diseases and Traumatology, 2019
Background: Drilling of the bone is common to produce holes for screws and pin insertion, to fix the fractured parts for immobilization. For this purpose, we need a power drill machine.
Sneh Prabhakar, Avtar Singh, Rajeev Vohra, Kanwar Kulwinder Singh, Inderdeep Singh   +4 more
doaj   +1 more source