Results 91 to 100 of about 564,345 (259)
Overview of equipment maintenance support mission planning model and solution [PDF]
Zhihui kongzhi yu fangzhenOur military’s exploration of equipment support mission planning is still in its infancy, traditional methods are difficult to meet the current equipment support needs, and there is an urgent need to combine with intelligent algorithms, machine learning ...
YANG Liangliang, ZHAO Deyong, LIU Xiaoyong, LIU Jie, SHEN Zixuan
doaj +1 more source
Experiment definition phase shuttle laboratory LDRL 10.6 experiment [PDF]
System optimization is reported along with mission and parameter requirements. Link establishment and maintenance requirements are discussed providing an acquisition and tracking scheme. The shuttle terminal configurations are considered and are included
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
IEEE Access, 2019 Selective maintenance is widely used as a reliability-centered maintenance strategy due to the limited maintenance resources. However, existing selective maintenance studies only consider basic reliability, which cannot systematically describe the ...
Zhaoxiang Chen +6 more
doaj +1 more source
Optimal maintenance of multi-component systems: a review [PDF]
In this article we give an overview of the literature on multi-component maintenance optimization. We focus on work appearing since the 1991 survey "A survey of maintenance models for multi-unit systems" by Cho and Parlar.
Dekker, R., Nicolai, R.P.
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Genetic and memetic algorithms for scheduling railway maintenance activities [PDF]
Nowadays railway companies are confronted with high infrastructure maintenance costs. Therefore good strategies are needed to carry out these maintenance activities in a most cost effective way.
Budai-Balke, G., Dekker, R., Kaymak, U.
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, 2013 A bi-level modelling approach is proposed to represent the interaction between the vehicle loading practices of road freight transport carriers, and the decisions of a road planning authority responsible both for road maintenance and for the enforcement ...
Fowkes, AS, Moreno, E, Watling, DP
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source