Results 81 to 90 of about 561,917 (307)
Optimal pavement management: Resilient roads in support of emergency response of cyclone affected coastal areas [PDF]
, 2019 Roads in poor road condition disrupt emergency operations in disaster-prone areas during emergency periods. Prolonged inundation of pavements from storm surge accelerates deterioration of pavements and increases maintenance cost.
Amador, Luis, Amin, Shohel, Tamima, Umma
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Vojnotehnički Glasnik, 1999 This work presents a possibility to find the optimum solution in the maintenance of high pressure pump systems when the criteria functions are maximal availability and minimal cost maintenance.
Ljubiša Brkić , Božidar V. Krstić
doaj +1 more source
Maintenance optimization of high voltage substation model [PDF]
, 2008 The real system from practice is selected for optimization purpose in this paper. We describe the real scheme of a high voltage (HV) substation in different work states. Model scheme of the HV substation 22 kV is demonstrated within the paper.
Briš, Radim, Gala, Jan
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Maintenance optimization of a production system with buffercapacity [PDF]
Marketing;Optimization;produktieleer ...
Vanneste, S.G.
core +1 more source
Optimal maintenance of multi-component systems: a review [PDF]
, 2006 In this article we give an overview of the literature on multi-component maintenance optimization. We focus on work appearing since the 1991 survey "A survey of maintenance models for multi-unit systems" by Cho and Parlar.
Dekker, R. (Rommert) +1 more
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
, 2013 A bi-level modelling approach is proposed to represent the interaction between the vehicle loading practices of road freight transport carriers, and the decisions of a road planning authority responsible both for road maintenance and for the enforcement ...
Fowkes, AS, Moreno, E, Watling, DP
core +1 more source