DoE Optimization of Applied Pressure and Mold Size in Manufacturing Homogeneous Alumina Samples by SPS Process under 1000A Current [PDF]
Journal of Applied and Computational MechanicsSpark plasma sintering (SPS) presents advantages over conventional sintering methods, notably high heating rates and reduced residence times. However, SPS suffers from uneven temperature and stress distributions due to suboptimal sintering parameters ...
Abdelmalek Kriba +3 more
doaj +1 more source
An Improved Optimization Algorithm for Aeronautical Maintenance and Repair Task Scheduling Problem
Mathematics, 2022 The maintenance of carrier-based aircraft is a critical factor restricting the availability of aircraft fleets and their capacity to sortie and operate.
Changjiu Li +3 more
doaj +1 more source
Data-Driven Application Maintenance: Views from the Trenches
, 2018 In this paper we present our experience during design, development, and pilot deployments of a data-driven machine learning based application maintenance solution.
Misra, Janardan +4 more
core +1 more source
Iterative design of dynamic experiments in modeling for optimization of innovative bioprocesses [PDF]
, 2009 Finding optimal operating conditions fast with a scarce budget of experimental runs is a key problem to speed up the development and scaling up of innovative bioprocesses. In this paper, a novel iterative methodology for the model-based design of dynamic
Cristaldi, Mariano Daniel +2 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Operational optimization of networks of compressors considering condition-based maintenance
, 2015 The paper presents a mixed integer linear programming model which deals with the optimal operation and maintenance of networks of compressors of chemical plants. This optimization model considers condition-based maintenance which involves the degradation
Cicciotti, M +3 more
core +1 more source
Genetic Algorithm for Job Scheduling with Maintenance Consideration in Semiconductor Manufacturing Process [PDF]
, 2012 This paper presents wafer sequencing problems considering perceived chamber conditions and maintenance activities in a single cluster tool through the simulation-based optimization method.
Lee, Seungchul, Ni, Jun
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Optimization in Knowledge-Intensive Crowdsourcing [PDF]
, 2014 We present SmartCrowd, a framework for optimizing collaborative knowledge-intensive crowdsourcing. SmartCrowd distinguishes itself by accounting for human factors in the process of assigning tasks to workers. Human factors designate workers' expertise in
Gautam Das +6 more
core +3 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source