Results 61 to 70 of about 156,578 (313)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A Periodicity Metric for Assessing Maintenance Strategies [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityThe maintenance policy in manufacturing systems is devised to reset the machines functionality in an economical fashion in order to keep the products quality within acceptable levels.
ElMaraghy, H. A.   +2 more
core  

Upgrading of a uniform system of technical material means maintenance in the ground forces

open access: yesVojnotehnički Glasnik, 2000
Under the conditions of technological modernization and constant development of material means, the macrosystem of maintenance of technical material means in the Ground Forces becomes more and more complex. Complexity of technical support in general, and
Branko Đedović
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An Interactive Decision Support System for Energy Management in Process Industry [PDF]

open access: yes, 2013
Industrial energy accounts for roughly one-third of total global energy consumption and is expected to continue with a similar share in the foreseeable future, therefore the efficient use of energy and energy saving are important issues for the ...
Darabnia, Behnoush
core   +1 more source

Mathematical Optimization of Wind Turbine Maintenance Using Repair Rate Thresholds

open access: yesAxioms
As reliance on wind energy intensifies globally, optimizing the efficiency and reliability of wind turbines is becoming vital. This paper explores sophisticated maintenance strategies, crucial for enhancing the operational sustainability of wind turbines.
Nataša Kontrec   +4 more
doaj   +1 more source

DoE Optimization of Applied Pressure and Mold Size in Manufacturing Homogeneous Alumina Samples by SPS Process under 1000A Current [PDF]

open access: yesJournal of Applied and Computational Mechanics
Spark plasma sintering (SPS) presents advantages over conventional sintering methods, notably high heating rates and reduced residence times. However, SPS suffers from uneven temperature and stress distributions due to suboptimal sintering parameters ...
Abdelmalek Kriba   +3 more
doaj   +1 more source

An Improved Optimization Algorithm for Aeronautical Maintenance and Repair Task Scheduling Problem

open access: yesMathematics, 2022
The maintenance of carrier-based aircraft is a critical factor restricting the availability of aircraft fleets and their capacity to sortie and operate.
Changjiu Li   +3 more
doaj   +1 more source

A Digital Twin Design for Maintenance Optimization

open access: yesProcedia CIRP, 2022
Digital Twin (DT) is being regarded as a suite of innovative technologies within the Industry 4.0 revolution. DT brings so much excitement to the industries pursuing digitalization. DT, as a real-time representation of a physical object supports manufacturers to enhance the yield from their operations. In particular, it offers a unique and advantageous
Davies, Oliver   +3 more
openaire   +2 more sources

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