Results 151 to 160 of about 1,638 (186)

Monoclonal platelet antigen capture assays (MAIPA) and reagents: a statement

Vox Sanguinis, 2007
This statement concerning the monoclonal‐specific immobilization of platelet antigens (MAIPA) has been written on behalf of the International Society of Blood Transfusion – Working Party on Platelet Immunology. The MAIPA technique is considered as the gold standard reference technique in platelet immunology.
C. Kaplan, J. Freedman, Z. Foxcroft, A. Husebekk, P. Metcalfe, E. Muñiz-Díaz, W. Ouwehand, S. Panzer, P. Rožman, B. Skogen   +9 more
semanticscholar   +4 more sources

Sensitivity of the platelet immunofluorescence test (PIFT) and the MAIPA assay for the detection of platelet‐reactive alloantibodies: a report on two U.K. National Platelet Workshop Exercises 1

Transfusion Medicine, 1994
SUMMARY. This report presents the results of two National Workshop exercises which were designed to evaluate interlaboratory and interassay variation in sensitivity of techniques used for the detection of platelet‐reactive alloantibodies. Most workshop participants used the platelet immunofluorescence test.
D. Allen, J. Chapman, P. Phillips, W. Ouwehand   +3 more
semanticscholar   +3 more sources

Comparison of the bead-based simultaneous analysis of specific platelet antibodies assay (SASPA) and Pak Lx Luminex technology with the monoclonal antibody immobilization of platelet antigens assay (MAIPA) to detect platelet alloantibodies

Clinical Chemistry and Laboratory Medicine (CCLM), 2015
AbstractThe identification of platelet alloantibodies is indispensible for the diagnoses of fetal/neonatal alloimmune thrombocytopenia and refractoriness to platelet transfusions.We compared the results obtained with the gold-standard assay for the detection and specification of platelet antibodies, the monoclonal antibody-specific immobilization of ...
Lisa Rockenbauer, B. Eichelberger, S. Panzer   +2 more
semanticscholar   +4 more sources

A comparison of monoclonal antibody immobilization of platelet antigen (MAIPA) and immunobead methods for detection of GPIIb/IIIa antiplatelet antibodies in immune thrombocytopenic purpura

Transfusion Medicine, 1997
In this study we have compared two assays for the detection of autoantibodies GpIIb/IIIa, platelet bound and in serum, in immune thrombocytopenic purpura (ITP). Both assays were found to have a similar sensitivity, but the monoclonal antibody immobilization of platelet antigen (MAIPA) assay was more reproducible than the immunobead assay. The MAIPA and
A. Crossley, J. Calvert, P. Taylor, A. Dickinson   +3 more
semanticscholar   +4 more sources

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Quantitative MAIPA: Comparison of different MAIPA protocols.

Transfusion and Apheresis Science, 2010
In a screening setting, maternal anti-HPA 1a antibody level has been found to be a good prognostic tool to identify newborns at risk for severe NAIT.Identify the optimal MAIPA protocol for quantitation of anti-HPA 1a antibodies.Plasma were analysed for anti-HPA 1a antibodies using different monoclonal antibodies, lyophilized or fresh platelets and ...
M. K. Killie, Wahida Salma, E. Bertelsen, B. Skogen, A. Husebekk   +4 more
semanticscholar   +3 more sources

Triple allo-immunisation plaquettaire materno-fœtale : cas clinique illustrant la complémentarité diagnostique du MAIPA et du Luminex

Transfusion Clinique et Biologique
Rachel Petermann, Marine Driessen, Yasmine Mammasse, Nicolas Ferre, P. Saulet, C. Chenet, Aurore Langry, F. Bianchi, Cécile Toly N’dour, Agnès Mailloux   +9 more
semanticscholar   +3 more sources

Incidence of autoantibodies to GPIIb/IIIa in chronic autoimmune thrombocytopenic purpura may be overestimated by the MAIPA

British Journal of Haematology, 1994
Summary Twenty‐one serum samples from patients with thrombocytopenia and five from normal individuals were analysed by the MAIPA test to determine specificity of autoantibody reactivity against platelet glycoprotein IIb/IIIa using murine monoclonal antibodies. The sera were also analysed by dot blot to determine their anti‐murine IgG activity.
J. Hewitt, I. Burton
semanticscholar   +3 more sources

Delayed detectability of anti‐HPA‐3a by the MAIPA assay in a severe neonatal alloimmune thrombocytopenia, but successful transfusion of incompatible donor platelets: a case report

Vox Sanguinis, 2006
Fetal/neonatal alloimmune thrombocytopenia (F/NAIT) is the most frequent cause of haemorrhagic morbidity and mortality in otherwise healthy term infants and occurs in 1 in 1000 to 1 in 2000 pregnancies [1]. Maternal HPA-1a alloimmunization is responsible for the majority of NAIT [1], and only a few cases of NAIT caused by anti-HPA-3a have been ...
K. Schallmoser, J. Kutschera, S. Macher, S. Ulrich, P. Eichler, S. Panzer, G. Lanzer   +6 more
semanticscholar   +3 more sources

Low incidence of specific anti‐platelet antibodies detected by the MAIPA assay in the serum of thrombocytopenic MDS patients and lack of correlation between platelet autoantibodies, platelet lifespan and response to danazol therapy

British Journal of Haematology, 1996
We prospectively studied the mechanism of thrombocytopenia in 30 patients with myelodysplastic syndrome (MDS), who had a platelet count ≤70×109/l , and marrow blasts ≤10% by analysis of platelet lifespan, platelet‐bound IgG antibodies by platelet radioactive antiglobulin test (PRAT), and circulating and platelet‐bound autoantibodies specifically ...
M. Hebbar, C. Kaplan, M. Caulier, E. Wattel, P. Morel, M. Wetterwald, F. Bauters, P. Fenaux   +7 more
semanticscholar   +3 more sources

10. MAIPA MADE ME DO IT

, 2017
Mark S. Mosko
semanticscholar   +2 more sources