Platelets, 1996 CD9 is a well-defined component of the platelet plasma membrane and has a copy number almost equivalent to that of glycoprotein (GP) IIb-IIIa complexes, the aggregation receptor on platelets. It has an apparent molecular mass of 24 kD and is otherwise known as p24.
J. Laroche-Traineau +5 more
semanticscholar +4 more sources
Platelet antibodies identification: comparison between two laboratory tests [PDF]
Hematology, Transfusion and Cell Therapy, 2022 Introduction: Platelet antibody identification is indispensable for diagnosing the human platelet antigen (HPA) or human leukocyte antigen (HLA) immunization, mostly because it can restrict the compatibility and results of transfusions. Correct detection
Valeria de Freitas Dutra +6 more
doaj +2 more sources
Journal of the Japan Society of Blood Transfusion, 2010 S. Kosugi +5 more
semanticscholar +4 more sources
Case Report: ITP Treatment After CAR-T Cell Therapy in Patients With Multiple Myeloma [PDF]
Frontiers in Immunology, 2022 Chimeric antigen receptor T (CAR-T) cell therapy is an attractive strategy for patients with relapsed or refractory hematological malignancies including multiple myeloma (MM). T cells are engineered to attack malignant cells that express tumor-associated
Mengyi Du +5 more
doaj +2 more sources
Platelet refractoriness due to combined anti‐HLA and anti‐HPA‐5a alloantibodies: clinical management during myeloablative allogeneic HSCT and development of a quantitative MAIPA assay [PDF]
British Journal of Haematology, 2007 C. Arber +5 more
semanticscholar +4 more sources
The interplay between GPIb/IX antibodies, platelet hepatic sequestration, and TPO levels in patients with chronic ITP. [PDF]
Blood Adv, 2023 Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder with an incompletely understood pathophysiology but includes platelet-clearance in the spleen and liver via T cells and/or platelet autoantibodies.
Amini SN +7 more
europepmc +3 more sources
Anti-Human Platelet Antigen-1a Immunoglobulin G Preparation Intended to Prevent Fetal and Neonatal Alloimmune Thrombocytopenia. [PDF]
PLoS ONE, 2016 Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a severe disease that is caused by maternal alloantibodies generated during pregnancy or at delivery as a result of incompatibility between maternal and fetal human platelet antigens (HPAs ...
Ying-Jan Weng +5 more
doaj +8 more sources
In vitro analysis of anti-HPA-1a dependent platelet phagocytosis and its inhibition using a new whole blood phagocytosis assay (WHOPPA) [PDF]
Frontiers in Immunology, 2023 Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a serious bleeding condition mostly caused by the reaction between maternal anti-HPA-1a antibodies and fetal platelets. This reaction leads to Fc-dependent platelet phagocytosis.
Paula Ames +11 more
doaj +2 more sources
Detection of Gov system antibodies by MAIPA reveals an immunogenicity similar to the HPA‐5 alloantigens [PDF]
British Journal of Haematology, 2000 The glycosylphosphatidylinositol‐linked platelet protein CD109 carries the biallelic alloantigen system Gov. There is limited information on the incidence of Gov alloantibodies in neonatal alloimmune thrombocytopenia (NAITP), post‐transfusion purpura (PTP) and platelet refractoriness.
J. Berry +11 more
semanticscholar +3 more sources
, 2012 published_or_final_version ; Medical Sciences ; Master ; Master of Medical ...
Sylvia Wong Yin-ki
openaire +3 more sources