Anti-glycoprotein antibodies and sequestration pattern of indium-labeled platelets in immune thrombocytopenia. [PDF]
Antiglycoprotein (anti-GP) antibodies play an important role in the pathophysiology of immune thrombocytopenia (ITP). The sequestration pattern of platelets in the spleen and liver can be studied with (111)In-labeled autologous platelet scans. No studies
Amini SN +6 more
europepmc +3 more sources
Flow cytometric immunobead assay for quantitative detection of platelet autoantibodies in immune thrombocytopenia patients [PDF]
Background Platelet autoantibody detection is critical for immune thrombocytopenia (ITP) diagnosis and prognosis. Therefore, we aimed to establish a quantitative flow cytometric immunobead assay (FCIA) for ITP platelet autoantibodies evaluation.
Juping Zhai +9 more
doaj +2 more sources
Novel method for simultaneously detecting HPA and HLA antibodies using Luminex microbeads [PDF]
Background Alloantibodies against human platelet antigens (HPAs) and human leukocyte antigen (HLA) are implicated in several immune-mediated platelet disorders.
Sudan Tao +4 more
doaj +2 more sources
Zuberitamab, an innovative anti-CD20 monoclonal antibody, for patients with primary immune thrombocytopenia in China: a randomized, double-blind, placebo-controlled, phase 2 studyResearch in context [PDF]
Summary: Background: Primary immune thrombocytopenia (ITP) is an autoimmune disease, and rituximab (RTX) induces long-term effect as second-line treatments.
Min Xu +16 more
doaj +2 more sources
Antibodies against Platelet Glycoproteins in Clinically Suspected VITT Patients. [PDF]
Vaccine-induced thrombotic thrombocytopenia (VITT) is a rare but severe complication following COVID-19 vaccination, marked by thrombocytopenia and thrombosis. Analogous to heparin-induced thrombocytopenia (HIT), VITT shares similarities in anti-platelet
Meier RT +11 more
europepmc +4 more sources
Som del av blodplatenes cellemembran inngår et antall glykoproteiner som medierer blodplatenes celle-celle-interaksjoner. Blodplatespesifikke alloantigen (Human platelet antigen, HPA) kan føre til immunisering og dannelse av alloantistoffer når mennesker som selv ikke utrykker disse molekylene på overflaten av sine blodplater, blir eksponert for dem ...
Renathe Nilsen
openaire +2 more sources
Improving prediction of fetal/neonatal intracranial hemorrhage in HPA-1a alloimmunized pregnancies to guide antenatal management: An observational cohort study. [PDF]
Pregnancies complicated by FNAIT‐related intracranial hemorrhage (ICH) in the fetus/newborn have significantly higher maternal anti‐HPA‐1a antibody levels compared to those without ICH. This opens up targeted antenatal treatment to avoid both under‐ and overtreatment.
Ernstsen SL +5 more
europepmc +2 more sources
MYH9-related disease: Assessment of the pathogenicity of a new mutation. [PDF]
eJHaem, Volume 4, Issue 3, Page 869-871, August 2023.
Antoine B +4 more
europepmc +2 more sources
Introduction: The highest quality and effectiveness of Cardiopulmonary Resuscitation (CPR) will be difficult to achieve if ventilatory assistance is provided using a Bag-Valve Mask (BVM) device and combined with compression by a single rescue. This study
Wirmando Wirmando +7 more
doaj +1 more source

