Results 51 to 60 of about 1,638 (186)

Circulating antiplatelet antibodies in pregnant women with immune thrombocytopenic purpura as predictors of thrombocytopenia in the newborns

Platelets, 2019
Newborns from mothers with immune thrombocytopenic purpura (ITP) have a risk of thrombocytopenia due to passage of maternal antiplatelet antibodies into fetal/neonatal circulation.
Svetlana G. Khaspekova, Olga N. Shustova, Nina V. Golubeva, Yaroslav A. Naimushin, Lyubov E. Larina, Alexey V. Mazurov   +5 more
doaj   +1 more source

Re-Evaluation Of Modified Rapid Monoclonal Antibody Immobilization Of Platelet Antigen (MR-MAIPA) For Detecting Platelet Antibody In Patients With Suspected Immune Thrombocytopenia [PDF]

, 2016
Ujian antibodi terhadap platelet di Malaysia hanya dijalankan di Pusat Darah Negara (PDN), Kuala Lumpur. Sebelum tahun 2013, ujian antibodi terhadap platelet di Malaysia dijalankan menggunakan teknik MAIPA. Namun begitu, MAIPA memerlukan masa selama tiga
Aziz, Mohd Fahmi
core  

COMPARAÇÃO DO TESTE DE DESIALIZAÇÃO PLAQUETÁRIA EM PACIENTES COM PÚRPURAS IMUNES E TROMBOCITOPATIAS CONGÊNITAS

Hematology, Transfusion and Cell Therapy
Introdução: As trombocitopatias congênitas como Trombastenia de Glanzmann (GT) e a Síndrome de Bernard-Soulier (BSS) são distúrbios hereditários raros provenientes de alterações quantitativas ou qualitativas da glicoproteína da membrana plaquetária GPIIb/
KNC Ziza, AMC Alves, MCAV Conrado, TCS Silva, C Gabe, P Villaça, V Rocha, A Mendrone-Junior, DL Júnior, J Bordin, CL Dinardo   +10 more
doaj   +1 more source

NF-κB-94ins/del ATTG Genotype Contributes to the Susceptibility and Imbalanced Th17 Cells in Patients with Immune Thrombocytopenia

Journal of Immunology Research, 2018
Background. The NLRP3 inflammasome plays important roles in the pathogenesis of autoimmune diseases. However, the role of the NLRP3 inflammasome in the pathophysiology of immune thrombocytopenia (ITP) remains unclear. Methods.
Jie Yu, Mingqiang Hua, Xueyun Zhao, Rui Wang, Chaoqing Zhong, Chen Zhang, Ruiqing Wang, Guosheng Li, Na He, Ming Hou, Daoxin Ma   +10 more
doaj   +1 more source

Perancangan Sandiwara Radio Legenda Masyarakat Sulawesi Selatan “cinta datu museng dan maipa deapati”

Jurnal Pendidikan dan Konseling (JPDK), 2022
Globalisasi merupakan proses masuknya kebudayaan dari satu negara ke negara lain tanpa dipengaruhi oleh ruang dan waktu. Globalisasi dapat memicu lahirnya imperialisme budaya, yang merupakan diterimanya budaya nasional pada satu negara. Indonesia merupakan negara yang mengalami dampak dari imperialism budaya, salah satu dengan masuknya budaya K-Pop ...
Permata , Jelita Lidia, Santoso, Jessica Budi, Hafsari, Mulfah Ayu Suci   +2 more
openaire   +1 more source

A Novel Engineering Cell Therapy Platform Mimicking the Immune Thrombocytopenia‐Derived Platelets to Inhibit Cytokine Storm in Hemophagocytic Lymphohistiocytosis

Advanced Science, Volume 11, Issue 45, December 4, 2024.
Inspired by the characteristics of platelets in immune thrombocytopenia that are easily phagocytosed by macrophages, this study designs and constructs anti‐CD41‐PLT‐VP16 for targeting abnormally activated macrophages in hemophagocytic lymphohistiocytosis (HLH).
Zhenyu Liu, Ying Du, Tong Zhou, Ting Qin, Yining Yuan, Weilu Xu, MengKun Fang, Xuemei Wang, Bing Chen, Peipei Xu   +9 more
wiley   +1 more source

Persistence of brucellosis in pastoral systems [PDF]

, 2013
Regarded as a highly contagious, zoonotic disease with worldwide distribution, brucellosis is endemic in many countries and settings and is responsible for a considerable economic and health-related burden.
Chitnis, N., Racloz, V., Roth, F., Schelling, E., Zinsstag, J.   +4 more
core   +1 more source

Informing pregnancy dose via target‐mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody

CPT: Pharmacometrics &Systems Pharmacology, Volume 13, Issue 11, Page 2002-2015, November 2024.
Abstract RLYB212 is a human monoclonal anti‐human platelet antigen (HPA)‐1a immunoglobulin gamma 1 in clinical development as a subcutaneous injection for the prevention of maternal alloimmunization to fetal HPA‐1a leading to fetal and neonatal alloimmune thrombocytopenia (FNAIT).
Courtney Moc Willeford, Krithika Shetty, Douglas Sheridan, Frank Engler   +3 more
wiley   +1 more source

In vitro expression analysis of the ITGB3 c.598G/A mutation and its association with FNAIT

Zhongguo shuxue zazhi
[Objective] To explore the role of the c.598G>A mutation of the ITGB3 gene in the occurrence of fetal and neonatal alloimmune thrombocytopenia (FNAIT) through its expression in vitro.
DING Haoqiang, YE Xin, XU Xiuzhang, XIA Wenjie, DENG Jing, LIU Jing, CHEN Yangkai, CHEN Dawei, XU Yaori   +8 more
doaj   +1 more source

A novel scoring model for predicting efficacy and guiding individualised treatment in immune thrombocytopaenia

British Journal of Haematology, Volume 205, Issue 3, Page 1108-1120, September 2024.
Summary Despite diverse therapeutic options for immune thrombocytopaenia (ITP), drug efficacy and selection challenges persist. This study systematically identified potential indicators in ITP patients and followed up on subsequent treatment. We initially analysed 61 variables and identified 12, 14, and 10 candidates for discriminating responders from ...
Min Xu, Jiachen Liu, Linlin Huang, Jinhui Shu, Qiuzhe Wei, Yu Hu, Heng Mei   +6 more
wiley   +1 more source