Results 161 to 170 of about 7,978,447 (307)

Major adverse cardiovascular events with remote ischemic conditioning and without remote ischemic conditioning.

, 2013
Major adverse cardiovascular events with remote ischemic conditioning and without remote ischemic conditioning.
Daniel Brevoord (313448), Peter Kranke (313449), Marijn Kuijpers (313450), Benedikt Preckel (313453), Nina Weber (313451), Markus Hollmann (313452)   +5 more
core   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

CYP2C19 Phenotype, P2Y12 Inhibitor Selection, and Clinical Outcomes in Patients on Maintenance Clopidogrel Therapy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Use of CYP2C19 genotyping to guide antiplatelet therapy is associated with improved clinical outcomes in patients naïve to P2Y12 inhibitors undergoing percutaneous coronary intervention.
Rajiv C. Patel, Cameron D. Thomas, Joseph S. Rossi, Francesco Franchi, Ellen C. Keeley, Amber L. Beitelshees, Julio D. Duarte, Luis Ortega‐Paz, Natasha Kulick, Marshall Winget, Anh B. Nguyen, William E. Yang, Sanjay Venkatesh, Dominick J. Angiolillo, Larisa H. Cavallari, Craig R. Lee, George A. Stouffer   +16 more
doaj   +1 more source

Current Progress of Studies of Coronary CT for Risk Prediction of Major Adverse Cardiovascular Event (MACE). [PDF]

J Cardiovasc Imaging, 2021
Zheng J, Lu B.
europepmc   +1 more source

Time-Dependent Risk for Recurrence in Survivors of Major Adverse Cardiovascular Events

Cureus
The prevalence of the population with a history of an occlusive cardiovascular event has been increasing in recent years, which means that a large number of patients will have a higher risk of presenting a fatal recurrence. The aim is to determine variables associated with time-to-recurrent cardiovascular events and analyze how changes in low-density ...
Bermon, Anderson, Trejo-Valdivia, Belem, Molina Castaño, Carlos Federico, Segura, Angela M, Serrano, Norma C   +4 more
openaire   +2 more sources

Major adverse cardiovascular events, intracerebral haemorrhage, and GI bleeding before and after PS matching.

, 2019
Major adverse cardiovascular events, intracerebral haemorrhage, and GI bleeding before and after PS matching.
Chaur-Jong Hu (125228), Chih-Hsin Muo (291210), You-Chia Chen (7325630), Dean Wu (4003010), Chung Y. Hsu (7255547), Amelia Nur Vidyanti (7325627), Lung Chan (3913255), Cheng-Li Lin (388859)   +7 more
core   +1 more source

Ultrasound‐Triggered piRNA Delivery Using Biomimetic Phase‐Changeable Nanoparticles for Theranostics of Myocardial Infarction

Advanced Science, EarlyView.
A biomimetic ultrasound‐responsive piRNA delivery nanoparticle platform (piR‐NPs) enables targeted delivery and ultrasound (US)‐triggered release of piR‐1873 in infarcted myocardium. The released piR‐1873 suppresses Usp2‐mediated RIP1/RIP3/MLKL necroptosis, reduces myocardial injury and fibrosis, and promotes cardiac functional recovery, providing a ...
Yajun Zhang, Hongzhao Qi, Yanyan Yang, Feng Wang, Tiantian Han, Yanbei Lei, Xiaolu Li, Zhibin Wang, Hua Qu, Tao Yu, Pin Sun   +10 more
wiley   +1 more source

Kinetics and Prognosis Value of CCL5/RANTES at the Acute Phase of ST‐Segment–Elevation Myocardial Infarction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background RANTES (regulated upon activation, normal T cell expressed, and secreted) or CCL5 (CC chemokine ligand 5) is a chemokine that mediates chemotaxis and activation of T cells, monocytes, mast cells, and dendritic cells.
Camille Brun, Florentin Moulin, Simon Leboube, Ahmad Hayek, Andrea Kaczmarczyk, Iyad Abou Saleh, Cyril Prieur, Yvonne Varillon, Eric Bonnefoy‐Cudraz, Nathan O. Mewton, Gabriel Bidaux, Claire Crola Da Silva, Melanie Paillard, Sylvie Ducreux, Thomas Bochaton   +14 more
doaj   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Impact of Testosterone Therapy on Major Cardiovascular Risk in Erectile Dysfunction Patients with Testosterone Deficiency

Research and Reports in Urology
Tanawin Poopuangpairoj, Kun Sirisopana, Chinnakhet Ketsuwan, Wisoot Kongchareonsombat, Yada Phengsalae, Wijittra Matang, Premsant Sangkum Division of Urology, Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok ...
Poopuangpairoj T, Sirisopana K, Ketsuwan C, Kongchareonsombat W, Phengsalae Y, Matang W, Sangkum P   +6 more
doaj