Results 151 to 160 of about 618,469 (262)

Closed‐Loop Decoding and Intervention of Pain: A Novel BMI Strategy Integrating θ‐Band Detection and Mechano‐Electro‐Biological Coupled Hydrogels

Advanced Science, EarlyView.
A closed‐loop brain–machine interface with a PFAPT hydrogel electrode identifies prefrontal θ‐band as a neuropathic pain biomarker. The hydrogel enables stable 28 d ECoG recording and delivers θ‐triggered cortical stimulation, alleviating pain and affective behaviors in rats via bidirectional regulation of inflammation and central sensitization ...
Yun Ji, Tao Li, Guoqiang Lei, Huichun Luo, Xiuqian Guo, Jiao Xiang, Tao Shi, Weitang Liu, Yuxin Zhang, Xiaoyu Liao, Shutao Zhao, Jiayun Wu, Wangao Zhang, Wenhui Liu, Chuanglong He, Shuo Chen, Tao Wu, Ke Ma   +17 more
wiley   +1 more source

Short-Term and Late-Term Effects of Psilocybin on Symptoms in Major Depression: A Randomized Clinical Trial.

JAMA Netw Open
Yngwe H, Plavén-Sigray P, Ekman CJ, Henje E, Berglund A, Tiger M, Beckman M, Lundberg J.   +7 more
europepmc   +1 more source

Visuomotor dysconnectivity as a candidate mechanism of psychomotor agitation in major depression. [PDF]

Psychol Med
Pokorny VJ, Anderson Z, Letkiewicz AM, Hirjak D, Walther S, Shankman S, Mittal V.   +6 more
europepmc   +1 more source

An Anterior Cingulate Cortex‐Anterior Insular Cortex Glutamatergic Circuit Gates Stress‐Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking

Advanced Science, EarlyView.
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang, Guangbing Duan, Huihui Sun, Zhiyu Dong, Qiwei Wang, Xiaowei Li, Ying Chen, Shuchang Xu, Ying Huang   +8 more
wiley   +1 more source

Association between Cortical Gyrification and Major Depression: Clinical Correlates.

Psychopathology
Buchmann A, Hase A, Ritter CJ, Müller ST, Haynes M, Ghisleni C, O Apos Gorman Tuura R, Kohler CS, Hasler G.   +8 more
europepmc   +1 more source

Lived Experiences and Engagement in an Exercise Program for People with Resistant Major Depression: TRACE-RMD Study. [PDF]

Healthcare (Basel)
Etxaniz-Oses J, Tous-Espelosin M, Sánchez P, Maldonado-Martín S, Prada-Perea AI, Iriarte-Yoller N.   +5 more
europepmc   +1 more source

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

Advanced Science, EarlyView.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen, Yu‐Xuan Weng, Zhi‐Xuan Xia, Yue‐Ling Zhao, Qian‐Qian Ding, Si‐Ying Wang, Ting Cao, Xuan‐Ying Chen, Wu‐Cheng Tao, Shen Lin, Zhou Chen, Yi‐Xiao Luo   +11 more
wiley   +1 more source

Adult ADHD with comorbid major depression shows a distinguishable polygenic pattern and negative cognitive style. [PDF]

Transl Psychiatry
Kranz TM, McNeill RV, Jacob CP, Ahrens KF, Neumann RJ, Plichta MM, Kollmann B, Streit F, Tüscher O, Lieb K, Weber H, Romanos M, Lesch KP, Reif A, Kittel-Schneider S, Ziegler GC.   +15 more
europepmc   +1 more source

Molecularly Engineered Wing‐Shaped Azobenzene Memristors for Logic‐in‐Memory and Edge Visual Intelligence

Advanced Science, EarlyView.
Rational engineering of terminal substituents in symmetric azobenzene‐based molecules enables precise control over conformationally coupled charge‐transfer processes. This design yields tunable nonvolatile resistive memory behaviors, ranging from write‐once‐read‐many‐times (WORM) to rewritable switching.
Yanze Liu, Tao Han, Jiahui Ding, Hong Lian, Lingling Yao, Zhaoxin Xu, Xingyu Zhang, Shuanglong Wang, Jiangnan Xia, Tianchi Zhang, Weiwei Kang, Qingchen Dong   +11 more
wiley   +1 more source

Late-onset major depression and subthreshold depressive symptoms as early clinical correlates of brain small vessel disease. [PDF]

Int J Neuropsychopharmacol
Mitkani CA, Tegos TJ, Kimiskidis VK, Koukou S, Fountoulakis KN.   +4 more
europepmc   +1 more source