Results 161 to 170 of about 618,469 (262)

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source

Author Correction: Intracranial directed connectivity links subregions of the prefrontal cortex to major depression. [PDF]

Nat Commun
Myers J, Xiao J, Mathura RK, Shofty B, Gates V, Adkinson J, Allawala AB, Anand A, Gadot R, Najera R, Rey HG, Mathew SJ, Bijanki K, Banks G, Watrous A, Bartoli E, Heilbronner SR, Provenza N, Goodman WK, Pouratian N, Hayden BY, Sheth SA.   +21 more
europepmc   +1 more source

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

Advanced Science, EarlyView.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang, Shuhan Duan, Qiuxia Sun, Renkuan Tang, Lintao Luo, Jie Zhong, Zhaxylyk Sabitov, CAGDP Consortium†, Lan‐Hai Wei, Chao Liu, Maxat Zhabagin, Guanglin He   +11 more
wiley   +1 more source

Reduced circulating progenitor cells in older adults with major depression: Evidence of accelerated biological aging. [PDF]

Brain Behav Immun Health
Vieira EL, El-Ahmad P, Nikolova Y, Rajji T, Diniz BS.   +4 more
europepmc   +1 more source

Radiation Resilient Synthetic Antiferromagnets‐Based Neuromorphic Device for Sea Surface Temperature Reconstruction

Advanced Science, EarlyView.
By leveraging strong antiferromagnetic coupling, radiation‐tolerant synthetic antiferromagnetic synaptic devices are developed. Their intrinsic nonlinearity emulates neuronal activation, while linear and symmetric conductance modulation mimics synaptic plasticity.
Mingxu Song, Jiahao Liu, Ruisheng Hu, Teng Xu, Aihua Tang, Zhihong Zhu   +5 more
wiley   +1 more source

Major depression and mortality from cancer: a 10-year Italian study

European Psychiatry
Luigi Grassi, Elisa Stivanello, Martino Belvederi Murri, Marco Cruciata, Angela Muscettola, Vincenza Perlangeli, Paolo Pandolfi, Barbara Zaccagnino, Elena Meggiolaro, Federica Ruffilli, Marco Menchetti, Ilaria Panzini, Domenico Berardi, Rosangela Caruso   +13 more
doaj   +1 more source

Circuit-targeted modulation of anxiety symptoms in individuals with major depression: A randomized head-to-head TMS trial. [PDF]

Mol Psychiatry
Taylor JJ, Li J, Lin C, Jones E, Frandsen S, Becker CR, Drew W, Haj-Darwish D, Jabbour S, Leach J, Palm S, Sanderson L, Santos E, Sterina L, Chiulli N, Miller J, Barantono S, Gonsalvez I, Lyndon S, Snider SB, Fox MD, Siddiqi SH.   +21 more
europepmc   +1 more source

An Immediate‐Response Detection System for γ‐Hydroxybutyrate to Enhance Personal Safety in Social Environments

Advanced Science, EarlyView.
A graphene‐based electrical biosensor enables rapid and highly sensitive detection of GHB at 100 fm in both standard solutions and artificial urine, providing reliable point‐of‐need screening for drug‐facilitated sexual assault. The platform demonstrates strong selectivity, fast response, and a wide dynamic range, supporting accurate detection in ...
Jai Eun An, Jisung Kwak, Kyung Ho Kim, Chaeeun Kim, Sung Eun Seo, Nathaniel S. Hwang, Yong‐Sang Ryu, Hyun Seok Song, Oh Seok Kwon   +8 more
wiley   +1 more source

Application of Treatment Response Biomarkers from Major Depression to Perinatal Depression. [PDF]

J Pers Med
Kwok W, Wagner-Schuman M, Eisenlohr-Moul T, Hage B.   +3 more
europepmc   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source