Results 131 to 140 of about 827,746 (374)

The developmental trajectories of the behavioral phenotype and neuropsychiatric functioning in Cornelia de Lange and Rubinstein Taybi syndromes: A longitudinal study

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 2, Page 424-436, February 2023., 2023
Abstract Several changes in the behavioral phenotype arise with the growth of children affected by Cornelia de Lange Syndrome (CdLS) and Rubinstein‐Taybi Syndrome (RSTS). However, previous research relied on a cross‐sectional study design turning into age‐related comparisons of different syndromic cohorts to explore age‐dependent changes.
Paola Francesca Ajmone   +11 more
wiley   +1 more source

MFCC-based Recurrent Neural Network for Automatic Clinical Depression Recognition and Assessment from Speech [PDF]

open access: yesarXiv, 2019
Clinical depression or Major Depressive Disorder (MDD) is a common and serious medical illness. In this paper, a deep recurrent neural network-based framework is presented to detect depression and to predict its severity level from speech. Low-level and high-level audio features are extracted from audio recordings to predict the 24 scores of the ...
arxiv  

The reliability and validity of PHQ-9 in patients with major depressive disorder in psychiatric hospital

open access: yesBMC Psychiatry, 2019
Background To assess the reliability and validity of Patient Health Questionnaire-9 (PHQ-9) for patients with major depressive disorder (MDD) and to assess the feasibility of its use in psychiatric hospitals in China. Methods One hundred nine outpatients
Yue Sun   +5 more
semanticscholar   +1 more source

Maintenance deep transcranial magnetic stimulation sessions are associated with reduced depressive relapses in patients with unipolar or bipolar depression [PDF]

open access: yes, 2015
Introduction: Deep transcranial magnetic stimulation (dTMS) is a new form of TMS allowing safe stimulation of deep brain regions. The objective of this preliminary study was to assess the role of dTMS maintenance sessions in protecting patients with ...
ANGELETTI, Gloria   +11 more
core   +2 more sources

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

open access: yesAdvanced Science, EarlyView.
Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu   +12 more
wiley   +1 more source

Trial of SAGE-217 in Patients with Major Depressive Disorder.

open access: yesNew England Journal of Medicine, 2019
BACKGROUND Altered neurotransmission of γ-aminobutyric acid (GABA) has been implicated in the pathogenesis of depression. Whether SAGE-217, an oral, positive allosteric modulator of GABA type A receptors, is effective and safe for the treatment of major ...
H. Gunduz-Bruce   +13 more
semanticscholar   +1 more source

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

open access: yesAdvanced Science, EarlyView.
D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei   +18 more
wiley   +1 more source

Non-REM sleep in major depressive disorder

open access: yesNeuroImage: Clinical, 2022
Disturbed sleep is a key symptom in major depressive disorder (MDD). REM sleep alterations are well described in the current literature, but little is known about non-REM sleep alterations.
Leonore Bovy   +7 more
doaj  

Staging of Major Depressive Disorder [PDF]

open access: yes, 2017
Beekman, A.T.F. [Promotor]Penninx, B.W.J.H.
Verduijn, J.
core   +2 more sources

Sleep‐disordered breathing in major depressive disorder [PDF]

open access: yes, 2013
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99077/1/jsr12029 ...
Armitage, Roseanne   +5 more
core   +1 more source

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