Results 231 to 240 of about 832,143 (393)

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, EarlyView.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Positive memory enhancement training for individuals with major depressive disorder [PDF]

, 2018
De Raedt, Rudi, Hall, K. A. A., Joormann, Jutta, Timpano, Kiara R   +3 more
core   +2 more sources

Shared neurobiological changes in individuals with Crohn's disease and major depressive disorder. [PDF]

Commun Med (Lond)
Hartmann HA, Berthold ML, Ramkiran S, Bündgens L, Jaeger JW, Hagen J, Backhaus M, Collée M, Schnellbächer GJ, Veselinović T, Shah NJ, Schneider KM, Rajkumar R, Neuner I.   +13 more
europepmc   +1 more source

From stress to inflammation and major depressive disorder: a social signal transduction theory of depression.

Psychological bulletin, 2014
George M. Slavich, M. Irwin
semanticscholar   +1 more source

Dual‐Terminal Molecular Strategy for Robust and Reversible Supramolecular Adhesion

Advanced Science, EarlyView.
A minimalist supramolecular adhesive derived from a dual‐terminal molecule bearing carboxylic acid and triphenylphosphonium groups achieves strong, reversible adhesion through synergistic noncovalent interactions. The system exhibits rapid curing, broad substrate compatibility, and exceptional stability under solvents, humidity, and extreme ...
Shiru Wang, Liang Meng, Feng Li, Yuru Wang, Yongri Liang, Guangming Lu, Keju Sun, Yingdan Liu, Jingyue Yang   +8 more
wiley   +1 more source

Sertraline reduced the severity of patients' depressive symptoms in major depressive disorder [PDF]

, 2004
Karen Wagner, P Ambrosini, Moira A. Rynn, John S. March   +3 more
openalex   +1 more source

Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta‐analysis

World Psychiatry, 2015
D. Vancampfort, B. Stubbs, A. Mitchell, M. De Hert, M. Wampers, P. Ward, S. Rosenbaum, C. Correll   +7 more
semanticscholar   +1 more source

Nortriptyline Inhibits Lysosomal Exocytosis‐Mediated SASP During Gastric Cancer Progression via Targeting HOXA1‐PITX2 Phase Separation

Advanced Science, EarlyView.
This study identifies that HOXA1 facilitates transcriptional activity of PITX2 in liquid condensates, resulting in up‐regulation of MCOLN1 and RAB3A followed by lysosomal exocytosis of LGALS1 and IGFBP7 from senescent cells, thus activating AKT signaling and EMT.
Yi Zhou, Chunhui Yang, Xinyue Li, Xiaojing Wang, Wanju Jiao, Xiaolin Wang, Jiaying Qu, Bosen Zhao, Shunchen Zhou, Qiangsong Tong, Liduan Zheng   +10 more
wiley   +1 more source

Symptoms and Circuits, Part 1: Major Depressive Disorder

, 2003
Stephen M. Stahl
openalex   +2 more sources