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Ketamine for Major Depressive Disorder
2023Major Depressive Disorder (MDD) is a leading cause of disability worldwide. Conventional antidepressant treatment is characterised by a significant time to onset of therapeutic action (approximately 2 weeks) and fails to achieve a stable remission of symptoms in one-third of subjects with MDD.
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Situational Major Depressive Disorder
Archives of General Psychiatry, 1985Fifty-seven patients with situational major depression diagnosed by the Research Diagnostic Criteria were compared with 72 subjects with nonsituational major depression on demographic, clinical, and psychosocial variables. The situational patients tended to be younger and had fewer prior episodes of depression and fewer hospitalizations. No differences
R M, Hirschfeld +4 more
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Major depression and personality disorder
Journal of Affective Disorders, 1991The authors examined an interview and paper-and-pencil assessment of the DSM-III personality disorders (PDs) in depressed inpatients, and depressed relatives of psychiatric patients and never-ill controls who had a lifetime history of major depression. The rates of PDs according to the Structured Interview for DSM-III Personality Disorders (SIDP) were ...
M, Zimmerman +4 more
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New Directions for Mental Health Services, 1992
AbstractMajor depressive disorder (MDD) is now an accepted disorder in children and adolescents; genetic studies and data that support a dysregulation of one or more neurotransmitter systems suggest that biological factors play an important role in MDD in children and adolescents.
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AbstractMajor depressive disorder (MDD) is now an accepted disorder in children and adolescents; genetic studies and data that support a dysregulation of one or more neurotransmitter systems suggest that biological factors play an important role in MDD in children and adolescents.
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Major Depressive Disorder in a Preschooler
Journal of the American Academy of Child Psychiatry, 1985The history and evaluation of a preschool child who meets criteria for major depressive disorder are reported. In addition to describing the multifaceted workup required, the authors acknowledge the developmental issues which makes the diagnosis of depression difficult in this age group.
J H, Kashani, G A, Carlson
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Subtyping Major Depressive Disorder
Psychotherapy and Psychosomatics, 2010during their lifetime in epidemiological studies using current criteria [4] . It is unlikely that a syndrome as polymorphic and widely diagnosed as major depressive disorder (MDD) will reflect a single process. Attempts to delineate different forms of depression by statistically analyzing the symptomatology of large samples of patients without taking ...
Pesach, Lichtenberg, R H, Belmaker
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Hypersomnia in major depressive disorders
Journal of Affective Disorders, 1984Hypersomnia was experienced by 17 of 102 patients with major depressive disorder. Comparisons between hypersomnic and non-hypersomnic depressives demonstrated significant associations between hypersomnia and increased appetite, weight gain, agitation, headaches, depression in a first-degree relative, and earlier age of illness onset.
M J, Garvey, D, Mungas, G D, Tollefson
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MicroRNAs in Major Depressive Disorder
2019Major depressive disorder (MDD) is a severe and chronic psychiatric disorder with a high prevalence in the population. Although our understanding of its pathophysiological mechanisms has significantly increased over the years, available treatments still present several limitations and are not effective to all MDD patients.
Gabriel R, Fries +3 more
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Journal of Psychiatric Research, 2015
Subcortical gray matter regions have been implicated in mood disorders, including Major Depressive Disorder (MDD) and Bipolar Disorder (BD). It is unclear, however, whether or how these regions differ among mood disorders and whether such abnormalities are state- or trait-like.
Matthew D, Sacchet +4 more
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Subcortical gray matter regions have been implicated in mood disorders, including Major Depressive Disorder (MDD) and Bipolar Disorder (BD). It is unclear, however, whether or how these regions differ among mood disorders and whether such abnormalities are state- or trait-like.
Matthew D, Sacchet +4 more
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Major Depression, Double Depression and Personality Disorders
Journal of Personality Disorders, 2000Personality disorders are much more common among depressive patients than among normal people. Until now, little research has been conducted into the prevalence of personality disorders among patients with both major depression and dysthymia (double depression).
S, Kool +3 more
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