Results 271 to 280 of about 193,331 (298)
Some of the next articles are maybe not open access.
MicroRNAs in Major Depressive Disorder
2019Major depressive disorder (MDD) is a severe and chronic psychiatric disorder with a high prevalence in the population. Although our understanding of its pathophysiological mechanisms has significantly increased over the years, available treatments still present several limitations and are not effective to all MDD patients.
Deborah Benevenuto +3 more
openaire +3 more sources
Epigenetics of Major Depressive Disorder
2020Epigenetic modifications can alter gene expression through mechanisms that are heritable, but do not involve direct changes in the nucleotide sequence of the genome. Recent findings have suggested that epigenetic modifications are associated with several psychiatric disorders.
Wang K. Z. +6 more
openaire +1 more source
Ketamine for Major Depressive Disorder
2023Major Depressive Disorder (MDD) is a leading cause of disability worldwide. Conventional antidepressant treatment is characterised by a significant time to onset of therapeutic action (approximately 2 weeks) and fails to achieve a stable remission of symptoms in one-third of subjects with MDD.
openaire +2 more sources
Hormones and Major Depressive Disorder
2019Hormonal influences figure prominently in the development of major depressive disorder (MD). The chapter addresses the hypothalamic-pituitary-adrenal (HPA) axis and gonadal (i.e., estrogen and testosterone) hormones that are most relevant to MD. There is substantial evidence of HPA dysfunction in persons with MD, including adrenal hypersensitivity ...
Mark A. Ellenbogen +2 more
openaire +2 more sources
Tunable Chemical Disorder in Concentrated Alloys: Defect Physics and Radiation Performance
Chemical Reviews, 2022William J Weber +2 more
exaly