Major Depressive Disorder: A General Overview [PDF]
SHS Web of ConferencesMajor Depressive Disorder (MDD) has become a serious mental health problem with a lifetime prevalence of 15% to 20%. MDD is associated with significant morbidity, mortality, disability, and negative influence on patient's daily life This article is an ...
Wang Tianqi
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Sparse whole-genome sequencing identifies two loci for major depressive disorder. [PDF]
, 2015 Major depressive disorder (MDD), one of the most frequently encountered forms of mental illness and a leading cause of disability worldwide, poses a major challenge to genetic analysis.
CONVERGE consortium
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Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang +7 more
wiley +1 more source
Neuroinflammatory Hypothesis in Major Depressive Disorder
Psikiyatride Güncel Yaklaşımlar, 2014 Faced with stress and acute instances, brain cells trigger neuroinflammation and increase inflam-mation response and can cause cell damage, cell death and thereby functional insufficiencies, behavioral disorders and autonomic imbalances.
Gulfizar Sozeri-Varma
doaj +1 more source
Hidden scars in depression? Implicit and explicit self-associations following recurrent depressive episodes [PDF]
, 2013 To help explain the recurrent nature of major depressive disorder, we tested the hypothesis that depressive episodes and/or the duration of depressive symptoms may give rise to persistent dysfunctional implicit and/or more explicit self-associations ...
Bockting, Claudi LH +4 more
core +3 more sources
Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim +3 more
wiley +1 more source
Indian Journal of Psychological MedicineBackground: Inflammatory cytokines are associated with the pathophysiology of major depressive disorder (MDD). Nevertheless, whether they are trait or state biomarkers remains unclear.
Christopher Rockson +3 more
doaj +1 more source
Depressive disorders in caregivers of dementia patients: a systematic review. [PDF]
, 2005 Although depressive symptomatology has been well studied in caregivers of patients with dementia, depressive disorders have been examined much less.
Anderson IM +12 more
core +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
THE IMPACT OF DISPLACEMENT ON THE EXPRESSION OF DEPRESSIVE DISORDER AND SOCIAL FUNCTIONING AMONG THE WAR REFUGEES [PDF]
, 2009 Our research objective was to estimate the characteristics of major depressive disorder and social adaptation of women displaced during the war in Croatia in the early 1990s.
Anamarija Petek +6 more
core +1 more source