Results 41 to 50 of about 6,214,949 (261)

Distinguish bipolar and major depressive disorder in adolescents based on multimodal neuroimaging: Results from the Adolescent Brain Cognitive Development study

open access: yesDigital Health, 2022
Background Major depressive disorder and bipolar disorder in adolescents are prevalent and are associated with cognitive impairment, executive dysfunction, and increased mortality. Early intervention in the initial stages of major depressive disorder and
Yujun Liu   +9 more
doaj   +1 more source

Epigenetics of major depressive disorder

open access: yes, 2019
Epigenetic modifications can alter gene expression through mechanisms that are heritable, but do not involve direct changes in the nucleotide sequence of the genome. Recent findings have suggested that epigenetic modifications are associated with several
Dada O. O.   +6 more
core   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova   +9 more
wiley   +1 more source

Magnetic resonance spectroscopy in the evaluation of treatment efficacy in unipolar major depressive disorder: a review of the literature [PDF]

open access: yes, 2012
More and more neuroimaging studies are using in vivo proton magnetic resonance spectroscopy (1H-MRS) to explore correlates of response to therapy in major depressive disorder (MDD). Their aim is to further understanding of the effects of neurotransmitter
A. Pichiecchio   +18 more
core   +1 more source

Unit Cost of Major Depressive Disorder in Psychiatric Ward, Siriraj Hospital

open access: yesSiriraj Medical Journal, 2005
Objective: To study the unit cost of treatment of major depressive disorder patients who were admitted into the psychiatric ward in Siriraj Hospital in fiscal year 2001. Methods: This is a retrospective study from the view of care providers.
Suwit Charoensak   +3 more
doaj  

A Comparison of Sexual Dysfunctions in Female Patients with Major Depressive Disorder and Panic Disorder

open access: yesBilişsel Davranışçı Psikoterapi ve Araştırmalar Dergisi, 2014
Objective: The aim of this study is assessment of sexual dysfunction in female patients with major depressive disorder and panic disorder and compare the two groups. Methods: Total 76 female patients with primary diagnosis of major depressive disorder (
Tonguç Demir Berkol   +5 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon   +9 more
wiley   +1 more source

A retrospective analysis to estimate the healthcare resource utilization and cost associated with treatment-resistant depression in commercially insured US patients.

open access: yesPLoS ONE, 2020
ObjectiveThe economic burden of commercially insured patients in the United States with treatment-resistant depression and patients with non-treatment-resistant major depressive disorder was compared using data from the Optum Clinformatics™ claims ...
Gang Li   +7 more
doaj   +2 more sources

Decreased gyrification in major depressive disorder

open access: yes, 2009
Structural and functional abnormalities have been extensively reported in major depressive disorder, but possible changes in cortical folding have not yet been explored in this disorder.
Yu, Chunshui   +6 more
core   +1 more source

Executive functions in major depressive disorder

open access: yesSri Lanka Journal of Psychiatry, 2018
BackgroundIt is reported that executive functions are impaired in a variety of neuropsychiatric syndromes, including depressive disorders. Studies on executive functions in depressive disorders are inconclusive.
K. Dhawan, C.Y. Sudarshan, S. Begum
doaj   +1 more source

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