Results 21 to 30 of about 519,976 (188)

Ketamine: A New Antidepressant? [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2015
Standart antidepressants are needed for the many individuals with major depressive disorder. However they do not respond adequately to treatment and because of a delay of weeks before the emergence of therapeutic effects.
Feride Karacaer
doaj   +1 more source

Real-world assessment of treatment inertia in the management of patients treated for major depressive disorder in the USA

open access: yesJournal of Comparative Effectiveness Research, 2023
Aim: Major depressive disorder (MDD) is a debilitating illness in which depressive symptoms may persist after treatment. Treatment inertia is the continued use of the same pharmacotherapy regimen when treatment goals are not met.
John J Sheehan   +6 more
doaj   +1 more source

Suicide‐specific mortality among patients with treatment‐resistant major depressive disorder, major depressive disorder with prior suicidal ideation or suicide attempts, or major depressive disorder alone

open access: yesBrain and Behavior, 2023
Background The impact of treatment‐resistant depression (TRD) or prior suicidal ideation/suicide attempt (SI/SA) on mortality by suicide among patients with major depressive disorder (MDD) is not well known. This retrospective, observational, descriptive
David M. Kern   +7 more
doaj   +1 more source

Failure of hippocampal deactivation during loss events in treatment-resistant depression [PDF]

open access: yes, 2015
Major depressive disorder is characterized by anhedonia, cognitive biases, ruminations, hopelessness and increased anxiety. Blunted responses to rewards have been reported in a number of recent neuroimaging and behavioural studies of major depressive ...
Blair A. Johnston   +8 more
core   +2 more sources

Brain aging in major depressive disorder

open access: yesEuropean Psychiatry, 2021
Depression and anxiety are common and often comorbid mental health disorders that represent risk factors for aging-related conditions. Brain aging has shown to be more advanced in patients with Major Depressive Disorder (MDD).
L. Han   +7 more
doaj   +1 more source

Prevalence and correlates of depressive disorders in people with Type 2 diabetes: results from the International Prevalence and Treatment of Diabetes and Depression (INTERPRET‐DD) study, a collaborative study carried out in 14 countries [PDF]

open access: yes, 2018
Aims To assess the prevalence and management of depressive disorders in people with Type 2 diabetes in different countries. Methods People with diabetes aged 18–65 years and treated in outpatient settings were recruited in 14 countries and underwent
Ahmed, H. U.   +39 more
core   +2 more sources

Sensor-AssistedWeighted Average Ensemble Model for Detecting Major Depressive Disorder [PDF]

open access: yes, 2019
The present methods of diagnosing depression are entirely dependent on self-report ratings or clinical interviews. Those traditional methods are subjective, where the individual may or may not be answering genuinely to questions.
Chang, Chuan-Yu   +6 more
core   +1 more source

Major depressive disorder in detention officers

open access: yesRevista de Saúde Pública, 2021
OBJECTIVE To identify factors associated with major depressive disorder (MDD) in detention officers. METHODS This cross-sectional study included all detention officers from the largest prison complex in the state of Bahia, Brazil.
Sheila Nascimento Santos   +3 more
doaj   +2 more sources

Comorbid depressive disorders in ADHD. the role of ADHD severity, subtypes and familial psychiatric disorders [PDF]

open access: yes, 2014
ObjectiveaaTo evaluate the presence of Major Depressive Disorder (MDD) and Dysthymic Disorder (DD) in a sample of Italian children with Attention Deficit Hyperactivity Disorder (ADHD) and to explore specific features of comorbid depressive disorders in ...
Andriola E   +6 more
core   +1 more source

What patients with bipolar disorder and major depressive disorder perceive as adverse life events precipitating a current major depressive episode

open access: yesSouth African Journal of Psychiatry, 2015
Background. Adverse life events (ALEs) as precipitants of a major depressive episode (MDE) have been the subject of many studies. These studies indicate an increase in ALEs in the 6 months preceding an MDE. Objectives.
Robyn Anne van Schoor, Pierre M Joubert
doaj   +1 more source

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