Results 11 to 20 of about 6,214,949 (261)

The association between genetically determined ABO blood types and major depressive disorder [PDF]

open access: yes, 2021
ABO blood types and their corresponding antigens have long been assumed to be related to different human diseases. So far, smaller studies on the relationship between mental disorders and blood types yielded contra-dicting results.
Pistis, Giorgio   +102 more
core   +1 more source

Genome-Wide Association Study of Major Depressive Disorder: New Results, Meta-Analysis, and Lessons Learned [PDF]

open access: yes, 2010
Major depressive disorder (MDD) is a common complex disorder with a partly genetic etiology. We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, 3673 screened controls and >1 M imputed single-nucleotide polymorphisms (SNPs)).
D I Boomsma   +142 more
core   +2 more sources

Putative Transcriptomic Biomarkers in the Inflammatory Cytokine Pathway Differentiate Major Depressive Disorder Patients from Control Subjects and Bipolar Disorder Patients [PDF]

open access: yes, 2014
Mood disorders consist of two etiologically related, but distinctly treated illnesses, major depressive disorder (MDD) and bipolar disorder (BPD). These disorders share similarities in their clinical presentation, and thus show high rates of misdiagnosis.
Farmer, A.   +76 more
core   +1 more source

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder [PDF]

open access: yes, 2015
Genetic risk prediction has several potential applications in medical research and clinical practice and could be used, for example, to stratify a heterogeneous population of patients by their predicted genetic risk.
Caesar, Sian   +958 more
core   +2 more sources

Lipidomics in Major Depressive Disorder

open access: yesFrontiers in Psychiatry, 2018
Omic sciences coupled with novel computational approaches such as machine intelligence offer completely new approaches to major depressive disorder (MDD) research.
Andreas Walther   +7 more
doaj   +1 more source

A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression.

open access: yesPLoS Genetics, 2019
Major depression is a common and severe psychiatric disorder with a highly polygenic genetic architecture. Genome-wide association studies have successfully identified multiple independent genetic loci that harbour variants associated with major ...
Zachary F Gerring   +3 more
doaj   +1 more source

Prevalence and risk factors of major depressive disorder in HIV/AIDS as seen in semi-urban Entebbe district, Uganda. [PDF]

open access: yes, 2011
BACKGROUND: Not much is known about the risk factors of major depressive disorder (MDD) in HIV/AIDS in the African socio-cultural context. Therefore a study was undertaken to examine the prevalence and risk factors of MDD in HIV/AIDS in semi-urban Uganda.
Vikram Patel   +14 more
core   +2 more sources

Serum level of soluble interleukin 6 receptor is a useful biomarker for identification of treatment‐resistant major depressive disorder

open access: yesNeuropsychopharmacology Reports, 2020
Aim A substantial proportion of major depressive disorder patients are treatment‐resistant to antidepressant therapy, who require augmentation drugs, or other treatments including electroconvulsive therapy or transcranial magnetic stimulation ...
Katsuhiko Yamasaki   +2 more
doaj   +1 more source

Do Suicide Attempts of Mood Disorder Patients Directly Increase the Risk for a Reattempt?

open access: yesFrontiers in Psychiatry, 2020
Background: Preceding suicide attempts strongly predict future suicidal acts. However, whether attempting suicide per se increases the risk remains undetermined.
Kari I. Aaltonen   +17 more
doaj   +1 more source

Depression: Special Considerations for the Dental Setting

open access: yesMedEdPORTAL, 2011
The 1-year prevalence rate for depression is 9.5%, or approximately 20.9 million adults in America. The lifetime prevalence of major depressive disorder is approximately 10%-25%.
Jessica G. Hinz
doaj   +1 more source

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