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Neurobiology of Major Depressive Disorder [PDF]
Neural Plasticity, 2013 We survey studies which relate abnormal neurogenesis to major depressive disorder. Clinically, descriptive gene and protein expression analysis and genetic and functional studies revised here show that individual alterations of a complex signaling ...Rosa Villanuevadoaj +3 more sourcesLipidomics in Major Depressive Disorder [PDF]
Frontiers in Psychiatry, 2018 Omic sciences coupled with novel computational approaches such as machine intelligence offer completely new approaches to major depressive disorder (MDD) research.Andreas Walther, Carlo Vittorio Cannistraci, Carlo Vittorio Cannistraci, Kai Simons, Claudio Durán, Mathias J. Gerl, Susanne Wehrli, Clemens Kirschbaum +7 moredoaj +3 more sourcesEpigenetics of major depressive disorder
, 2019 Epigenetic modifications can alter gene expression through mechanisms that are heritable, but do not involve direct changes in the nucleotide sequence of the genome. Recent findings have suggested that epigenetic modifications are associated with several Dada O. O., Bani-Fatemi A., De Luca V., Monda M., Graff A., Wang K. Z., Tasmim S. +6 morecore +2 more sourcesAffective Priming in Major Depressive Disorder [PDF]
Frontiers in Integrative Neuroscience, 2012 Research on cognitive biases in depression has provided considerable evidence for the impact of emotion on cognition. Individuals with depression tend to preferentially process mood-congruent material and to show deficits in the processing of positive ...Joelle eLeMoult, Joelle eLeMoult, K. Lira eYoon, Jutta eJoormann +3 moredoaj +3 more sourcesMajor depressive disorder [PDF]
Nature Reviews Disease Primers, 2016 Major depressive disorder (MDD) is a debilitating disease that is characterized by depressed mood, diminished interests, impaired cognitive function and vegetative symptoms, such as disturbed sleep or appetite. MDD occurs about twice as often in women than it does in men and affects one in six adults in their lifetime.Otte, Christian, Gold , Stefan M., Penninx, Brenda W., Pariante, Carmine Maria, Etkin, Amit, Fava, Maurizio, C. Mohr, David, Schatzberg , Alan +7 moreopenaire +5 more sourcesThe association between genetically determined ABO blood types and major depressive disorder [PDF]
, 2021 ABO blood types and their corresponding antigens have long been assumed to be related to different human diseases. So far, smaller studies on the relationship between mental disorders and blood types yielded contra-dicting results.Pistis, Giorgio, Tiemeier, H., Hamilton, Steven P., Garvert, Linda, Mors, Ole, Grabe, H., Tiemeier, H, Pistis, G., McIntosh, AM, Müller-Myhsok, B., Uher, R, Penninx, BWJH, Smoller, Jordan W., Boomsma, Dorret, Van der Auwera, Sandra, Martin, N.G., Potash, James B., Boomsma I, D., Hamilton, S.P., McIntosh, A., Uher, R., Grabe, HJ, Berger, K., Perlis, R.H., Berger, K, Martin, Nicholas G., Baune, Bernhard T., Mueller-Myhsok, Bertram, Magnusson, Patrik K. E., Lucae, S., Völzke, H., Greinacher, Andreas, Lewis, CM, Lewis, C.M., Garvert, L, Preisig, M, Smoller, JW, Mors, O., Müller-Myhsok, B, Völzke, H, Magnusson, PKE, Lewis, Cathryn M., Perlis, RH, McIntosh, Andrew M., Weissman, M., Uher, Rudolf, Garvert, L., Lucae, Susanne, Boomsma, DI, McIntosh, A.M., Preisig, Martin, Voelker, Uwe, Tiemeier, Henning, Perlis, R., Levinson, D.F., Weissman, MM, Breen, Gerome, Weissman, Myrna M., Perlis, Roy H., Shi, Jianxin, Berger, Klaus, Smoller, J., Weissman, M.M., Levinson, Douglas F., Rietschel, M, Breen, G, Mueller-Myhsok, B., Voelker, U., Preisig, M., Potash, JB, Lewis, C., Breen, G., Martin, NG, Grabe, H.J., Lucae, S, Potash, J.B., Boomsma, D.I., Penninx, Brenda W. J. H., Penninx, B., Greinacher, A., Grabe, Hans J., Rietschel, M., Martin, N., Baune, B., Smoller, J.W., Völker, U, Van der Auwera, S., Shi, J, Levinson, D., Greinacher, A, Shi, J., Potash, J., Voelzke, Henry, Hamilton, S., Rietschel, Marcella, Mors, O, Völker, U., Voelzke, H., Pistis, G, Magnusson, P., Baune, B.T., Baune, BT, Levinson, DF, Hamilton, SP, Van der Auwera, S +104 morecore +1 more sourceMajor Depressive Disorder [PDF]
Neuron, 2000 In summary, MDD is a highly prevalent major medical whose pathophysiology is still poorly understood. MDD is often recurrent or chronic, and evidence suggests that genetic factors partially influence overall risk of illness but also influence the sensitivity of individuals to the depressogenic effects of environmental adversity.Fava, Maurizio, Kendler, Kenneth Sopenaire +2 more sourcesGenome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned [PDF]
, 2010 Major depressive disorder (MDD) is a common complex disorder with a partly genetic etiology. We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, 3673 screened controls and >1 M imputed single-nucleotide polymorphisms (SNPs)). D I Boomsma, Maclean, A. W., Sullivan, P.F., Sullivan, P F, G Willemsen, de Geus, E.J.C., D J Statham, Willemsen, G.; id_orcid, Gordon, SD, Penninx, BWJH, Smit, J H, Medland, S E, Maclean, A.W., S E Medland, Penninx, B. W. J. H., van den Oord, E J C G, Montgomery, G W, Pergadia, M L, Byrne, E.M., Heath, A.C., Martin, N.G., MacIntyre, Donald; id_orcid, Hickie, I.B., Statham, D.J., C M Middeldorp, E M Byrne, B W J H Penninx, Nyholt, D.R., J J Hottenga, J H Smit, A K Henders, Blackwood, D.H., Liu, J. Z., N G Martin, A W Maclean, Lewis, C.M., Montgomery, G. W., McGuffin, P, S D Gordon, McEvoy, B.P., MacIntyre, D J, McGhee, K A, P A F Madden, MacIntyre, D J; id_orcid, Pergadia, M. L., van den Oord, E.J., McEvoy, B P, Gordon, S.D., Martin, N. G., D H R Blackwood, P F Sullivan, De Geus, E. J. C., Montgomery, G.W., Hottenga, J.J., Hickie, I. B., McGhee, K.A., Medland, S. E., C M Lewis, J Z Liu, Gordon, S D, Smit, J. H., Boomsma, D. I., Hottenga, J. J., Smit, J.H., Middeldorp, C.M., Ripke, S., M L Pergadia, Hickie, I B, de Geus, E.J., Wray, NR, Van Den Oord, E. J. C. G., Wray, N. R., Blackwood, DHR, de Geus, E J C, Penninx, B.W., B P McEvoy, McGhee, K. A., Middeldorp, C. M., Byrne, E. M., McEvoy, B. P., Macgregor, S, E J C G van den Oord, Statham, D J, Heath, A C, Lewis, C. M., van den Oord, E.J.C.G., I B Hickie, Willemsen, G., Pergadia, M.L., Medland, S.E., Sullivan, P. F., Penninx, B.W.J.H., Heath, A. C., Maclean, AW, Nyholt, D. R., N R Wray, S Macgregor, MacIntyre, DJ, Boomsma, D.I., G W Montgomery, Lewis, C M, Henders, A K, Madden, P. A. F., Madden, P.A.F., Henders, A.K., Hottenga, J J, McGuffin, P., Boomsma, D I, Madden, P.A., de Geus, E.J.C.; id_orcid, Oord, E.J.C.G. van den, Henders, A. K., Wray, N R, Madden, P A F, E J C de Geus, Pergadia, ML, D R Nyholt, Maclean, A W, Ripke, S, A C Heath, Ripke, Stephan, MacIntyre, D. J., Geus, E.J.C. de, Blackwood, D. H. R., Statham, D. J., Penninx, B W J H, Macgregor, S., Gordon, S. D., McGhee, KA, D J MacIntyre, Nyholt, D R, Wray, N.R., Middeldorp, C M, Liu, J Z, S Ripke, K A McGhee, P McGuffin, Nyholt, DR, Willemsen, G, Boomsma, D.I.; id_orcid, Lewis, C. M.; id_orcid, Martin, N G, Blackwood, D H R, Liu, J.Z., Byrne, E M, MacIntyre, D.J. +145 morecore +1 more sourcePutative Transcriptomic Biomarkers in the Inflammatory Cytokine Pathway Differentiate Major Depressive Disorder Patients from Control Subjects and Bipolar Disorder Patients [PDF]
, 2014 Mood disorders consist of two etiologically related, but distinctly treated illnesses, major depressive disorder (MDD) and bipolar disorder (BPD). These disorders share similarities in their clinical presentation, and thus show high rates of misdiagnosis.Farmer, A., Farmer, Anne E, Powell, Timothy R, Matthews Keith, Day, Richard K, Anne E. Farmer (215007), Powell Timothy R., Farmer, Anne E., Hosang Georgina M., Farmer Anne E., Martin, C, Leonard C. Schalkwyk (27674), Day, Richard K., Cohen-Woods Sarah, Katherine E. Tansey (128003), Cohen-Woods, Sarah, Richard K Day, Timothy R. Powell (533562), McGuffin Peter, Day Richard K., Farmer, AE, Matthews, K, Hosang, GM, Schalkwyk, Leonard, Schalkwyk, L., Timothy R Powell, Keith Matthews (22202), Tansey, Katherine E., Powell, TR, Matthews, K., Tansey, Katherine E, Powell, Timothy; id_orcid, Georgina M Hosang, Sarah Cohen-Woods (214940), Tansey, K., Martin, Charlotte, Martin, C., Hosang, Georgina, McGuffin, P., Tansey Katherine E., D'Souza Ursula M., Matthews, Keith, Leonard C Schalkwyk, Schalkwyk Leonard C., Charlotte Martin (533565), Day, RK, Matthews, Kieth, Anne E Farmer, Martin Charlotte, Hosang, G., D'Souza, Ursula M., Charlotte Martin, Powell, T., McGuffin, P, Schalkwyk, LC, Peter McGuffin, Tansey, KE, Georgina M. Hosang (533564), Ursula M D'Souza, Sarah Cohen-Woods, Schalkwyk, Leonard C., D'Souza, U., D'Souza, Ursula M, Keith Matthews, Peter McGuffin (51507), Day, R., Hosang, Georgina M., Katherine E Tansey, McGuffin, Peter, Ursula M. D'Souza (533563), Cohen-Woods, S, McGuffin, Peter W, Schalkwyk, Leonard C, Cohen-Woods, S., Powell, Timothy R., D'Souza, UM, Richard K. Day (533566) +76 morecore +1 more source
