Results 31 to 40 of about 322,474 (305)

Depression from the perspective of modern and Persian medicine

open access: yesElectronic Physician, 2018
Background: Depression is one of the five most-common diseases globally, and is expected to be the second leading cause of disability by 2020 and its economic and social burden is a major problem worldwide Objective: The aim of this research was to ...
Majid Anushiravani   +3 more
doaj   +1 more source

Prevalence and risk factors of major depressive disorder in HIV/AIDS as seen in semi-urban Entebbe district, Uganda. [PDF]

open access: yes, 2011
BACKGROUND: Not much is known about the risk factors of major depressive disorder (MDD) in HIV/AIDS in the African socio-cultural context. Therefore a study was undertaken to examine the prevalence and risk factors of MDD in HIV/AIDS in semi-urban Uganda.
Vikram Patel   +14 more
core   +1 more source

The Mistreatment of Major Depressive Disorder [PDF]

open access: yesThe Canadian Journal of Psychiatry, 2014
Objective: To examine the effects of classification on treatment in major depressive disorder (MDD). Method: This is a narrative review.
openaire   +2 more sources

Non-REM sleep in major depressive disorder

open access: yesNeuroImage: Clinical, 2022
Disturbed sleep is a key symptom in major depressive disorder (MDD). REM sleep alterations are well described in the current literature, but little is known about non-REM sleep alterations.
Leonore Bovy   +7 more
doaj   +1 more source

Retinoid homeostasis in major depressive disorder

open access: yesTranslational Psychiatry, 2023
The small, hormone-like molecule retinoic acid (RA) is a vital regulator in several neurobiological processes that are affected in depression. Next to its involvement in dopaminergic signal transduction, neuroinflammation, and neuroendocrine regulation ...
Lisa Rebecca Otto   +5 more
doaj   +1 more source

Immature defense mechanisms predict poor response to psychotherapy in major depressive patients with comorbid cluster B personality disorder

open access: yesBrazilian Journal of Psychiatry, 2022
Objective: To evaluate the impact of defense mechanisms at baseline on depressive symptoms after brief psychotherapies and after 6-months of follow-up among depressed patients with and without cluster B personality disorders (PDs).
Carolina Rheingantz Scaini   +8 more
doaj   +1 more source

Autobiographical Memories in Major Depressive Disorder [PDF]

open access: yesClinical Psychology & Psychotherapy, 2011
The objective of this research was to study the relation between the processing and recall of information in major depressive disorder. An autobiographical memory task was applied to 42 subjects with a diagnosis of major depressive disorder, 28 subjects with a diagnosis of panic disorder and 51 subjects without any psychological disorder.
Claúdio, Victor   +2 more
openaire   +4 more sources

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker   +11 more
wiley   +1 more source

Review: Escitalopram—translating molecular properties into clinical benefit: reviewing the evidence in major depression [PDF]

open access: yes, 2010
The majority of currently marketed drugs contain a mixture of enantiomers; however, recent evidence suggests that individual enantiomers can have pharmacological properties that differ importantly from enantiomer mixtures.
Taylor, David   +2 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

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