Results 51 to 60 of about 322,474 (305)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Predictors of recurrence of major depressive disorder

PLOS ONE, 2020
Un total de 201 patients atteints de trouble dépressif majeur provenant de quatre hôpitaux en Malaisie ont été suivis pendant 5 ans pour déterminer les facteurs pronostiques du trouble dépressif majeur récurrent qui pourraient potentiellement contribuer à améliorer la prise en charge des patients atteints de TDM.
Munn‐Sann Lye, Yin-Yee Tey, Yin Sim Tor, Aisya Farhana Shahabudin, Normala Ibrahim, King‐Hwa Ling, Johnson Stanslas, Su Peng Loh, Rozita Rosli, Khairul Aiman Bin Lokman, Ibrahim Mohammed Badamasi, Asraa Faris-Aldoghachi, Nurul Asyikin Abdul Razak   +12 more
openaire   +4 more sources

Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach

, 2022
Background Response to lithium in patients with bipolar disorder is associated with clinical and transdiagnostic genetic factors. The predictive combination of these variables might help clinicians better predict which patients will respond to lithium ...
Streit, Fabian, Ardau, Raffaella, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Akula, Nirmala, Cearns, Micah, Akiyama, Kazufumi, Frank, Joseph, Thalamuthu, Anbupalam, Adli, Mazda, Amare, Azmeraw T., Baune, Bernhard T., Schubert, Klaus Oliver   +11 more
core   +1 more source

Distinguish bipolar and major depressive disorder in adolescents based on multimodal neuroimaging: Results from the Adolescent Brain Cognitive Development study

Digital Health, 2022
Background Major depressive disorder and bipolar disorder in adolescents are prevalent and are associated with cognitive impairment, executive dysfunction, and increased mortality. Early intervention in the initial stages of major depressive disorder and
Yujun Liu, Kai Chen, Yangyang Luo, Jiqiu Wu, Qu Xiang, Li Peng, Jian Zhang, Weiling Zhao, Mingliang Li, Xiaobo Zhou   +9 more
doaj   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Unit Cost of Major Depressive Disorder in Psychiatric Ward, Siriraj Hospital

Siriraj Medical Journal, 2005
Objective: To study the unit cost of treatment of major depressive disorder patients who were admitted into the psychiatric ward in Siriraj Hospital in fiscal year 2001. Methods: This is a retrospective study from the view of care providers.
Suwit Charoensak, Sunanta Chantarujikapong, Suthichai Cherdsuwan, Kanokkan Ontale   +3 more
doaj  

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

A retrospective analysis to estimate the healthcare resource utilization and cost associated with treatment-resistant depression in commercially insured US patients.

PLoS ONE, 2020
ObjectiveThe economic burden of commercially insured patients in the United States with treatment-resistant depression and patients with non-treatment-resistant major depressive disorder was compared using data from the Optum Clinformatics™ claims ...
Gang Li, Ling Zhang, Allitia DiBernardo, Grace Wang, John J Sheehan, Kwan Lee, Johan Reutfors, Qiaoyi Zhang   +7 more
doaj   +2 more sources

Cognitive behavior therapy in panic disorder and comorbid major depression - A naturalistic study [PDF]

, 2000
Background: There is a lack of evidence about the effectiveness of cognitive behavior therapies (CBT) in settings of routine clinical care as well as in the treatment of panic and comorbid disorders. Methods: We investigated a group-oriented CBT approach
Fichter, Manfred M., Trenkamp, Susanne, Rief, Winfried, Auer, Claudia   +3 more
core   +1 more source