Results 241 to 250 of about 239,963 (355)

Bioengineered Extracellular Vesicles in Emerging Cancer Vaccine Platforms

Small Science, EarlyView.
This review highlights recent advances in engineering extracellular vesicles (EVs) as next‐generation cancer vaccines. It outlines their biological roles and antigen‐presenting capacity, explores key strategies for antigen loading and delivery optimization, and summarizes preclinical and clinical applications using EVs from diverse immune and tumor ...
Wonkyung Ahn, Yeram Lee, Gi‐Hoon Nam, Jae Bem You, Eun Jung Lee   +4 more
wiley   +1 more source

New mutations and new phenotypes: a case of Major Histocompatibility Complex Class II Deficiency. [PDF]

Immunol Res
Li X, Lu B, Luo X.
europepmc   +1 more source

Class II genes of the human major histocompatibility complex. Evolution of the DP region as deduced from nucleotide sequences of the four genes.

, 1987
Kenth Gustafsson, E Widmark, Ann-Kristin Jonsson, B Servenius, D H Sachs, Dan Larhammar, Lars Rask, P A Peterson   +7 more
openalex   +1 more source

Immune Activation in Primary Sclerosing Cholangitis: A Systematic Review and Comparative Analysis With Inflammatory Bowel Diseases

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background and Objectives Primary sclerosing cholangitis (PSC) is a chronic liver disease with aberrant immune dysregulation and bile duct fibrosis. It is often associated with inflammatory bowel disease (IBD), especially ulcerative colitis, raising questions about distinct immune activation in these conditions.
Md Moniruzzaman, Ayesha Shah, Thomas Fairlie, Simon Keely, Grace L. Burns, Nicholas Talley, Gerald Holtmann   +6 more
wiley   +1 more source

Deletion of metal transporter Zip14 reduces major histocompatibility complex II expression in murine small intestinal epithelial cells. [PDF]

Proc Natl Acad Sci U S A
Jimenez-Rondan FR, Ruggiero CH, Riva A, Yu F, Stafford LS, Cross TR, Larkin J, Cousins RJ.   +7 more
europepmc   +1 more source

A CLASS II MONOCLONAL ANTIBODY SPECIFIC FOR THE RT1.B, RATHER THAN THE RT1.D, PRODUCT OF THE RAT MAJOR HISTOCOMPATIBILITY COMPLEX

, 1983
Audrey J. Goldner-Sauvé, Abraham Fuks, Ronald D. Guttmann, Donald V. Cramer   +3 more
openalex   +1 more source

Human skin‐derived micronized acellular dermal matrix modulates angiogenesis to enhance tissue reconstruction

VIEW, EarlyView.
Angiogenesis is an essential process in tissue regeneration, as it prevents complications such as necrosis, inflammation, and fibrosis. mADM decellularized by the supercritical carbon dioxide method exhibits high preservation of the extracellular matrix and various growth factors.
Hyo‐Jin Kim, Won‐Hong Min, Soohyun Kim, Duri Lee, Jin Woo Bae, Yongwoo Shin, Kyusup An, Bo‐Gyeong Seo, Won‐bin Jo, Kwang Dong Kim, Jiyun Yoo, Hyuk‐Kwon Kwon, Jeong‐Hyung Lee, Ki Yong Hong, Cheol Hwangbo   +14 more
wiley   +1 more source

Targeted and complete genomic sequencing of the major histocompatibility complex in haplotypic form of individual heterozygous samples. [PDF]

Genome Res
Hu T, Mosbruger TL, Tairis NG, Dinou A, Jayaraman P, Sarmady M, Brewster K, Li Y, Hayeck TJ, Duke JL, Monos DS.   +10 more
europepmc   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Contribution of major histocompatibility complex class II immunostaining in distinguishing idiopathic inflammatory myopathy subgroups: A histopathological cohort study. [PDF]

J Neuropathol Exp Neurol
Lessard LER, Robert M, Fenouil T, Mounier R, Landel V, Carlesimo M, Hot A, Chazaud B, Laumonier T, Streichenberger N, Gallay L.   +10 more
europepmc   +1 more source