Results 251 to 260 of about 680,011 (354)

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

The Role of the Major Histocompatibility Complex Region on Chromosome 6 in Skin Atrophy: A Mendelian Randomization Study. [PDF]

J Cosmet Dermatol
Zhao C, Fan Z, Zhang R, Sun Y, Li WY.
europepmc   +1 more source

A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations.

, 1993
Joseph Dal Porto, Teit E. Johansen, Branimir Čatipović, D J Parfiit, David A. Tuveson, Ulrik Gether, Steven Kozlowski, Douglas T. Fearon, Jonathan P. Schneck   +8 more
openalex   +2 more sources

Characterization and evolution of MHC II genes in the European eel (Anguilla anguilla) [PDF]

, 2013
Bracamonte, Seraina E.
core  

Advances and Prospects of Stereotactic Radiosurgery and Stereotactic Ablative Body Radiotherapy: Evolving Paradigms in Precision Oncology

Med Research, EarlyView.
The graphical abstract outlines the progressive development and impact of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Technological Evolution illustrates the transition from brachytherapy with single‐dose, LDR/HDR schedules to fractionated radiotherapy, three‐dimensional conformal radiotherapy (3DCRT) and Gamma Knife ...
Jing Zhang, Wenhao Xu, Weiqing Lu, Yingxuan Lin, Luoxi He, Zonglin Lv, Yiliyaer Nuerrula, Zouting, Zhen Zhang, Hailiang Zhang, Xuejun Ma   +10 more
wiley   +1 more source

A roadmap for T cell receptor-peptide-bound major histocompatibility complex binding prediction by machine learning: glimpse and foresight. [PDF]

Brief Bioinform
Qi F, Huang Q, Xuan Y, Cao Y, Shen Y, Ren Y, Liu Z, Zhang Z.   +7 more
europepmc   +1 more source

Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection.

Proceedings of the National Academy of Sciences of the United States of America, 1989
A. Hughes, M. Nei
semanticscholar   +1 more source

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

Movement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark, Hannah A. Staley, Ann M. Titus, Julian Agin‐Liebes, Alicia Garrido, Laura Hughes, Nicolas Dzamko, Rebecca L. Wallings, Malú Gámez Tansey   +8 more
wiley   +1 more source

Using major histocompatibility complex (MHC) II expression to predict antitumor response to CD4 + lymphocyte depletion. [PDF]

Sci Rep
Wang Y, Kim M, Su S, Halwatura L, You S, Kim HL.   +5 more
europepmc   +1 more source

Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation.

Cell Metabolism, 2013
Tuo Deng, Christopher J. Lyon, L. Minze, Jianxin Lin, Jia Zou, Joey Liu, Yuelan Ren, Zheng Yin, D. Hamilton, P. Reardon, Vadim Sherman, Helen Y Wang, K. Phillips, P. Webb, Stephen T. C. Wong, Rong-Fu Wang, W. Hsueh   +16 more
semanticscholar   +1 more source