Results 261 to 270 of about 242,210 (352)

Research progress in the application of single‐cell sequencing technology in rheumatic diseases

Rheumatology &Autoimmunity, EarlyView.
Application of single‐cell RNA sequencing (scRNA‐seq) technology in the study of the pathogenesis of rheumatic diseases. Tree of content illustration depicting the multi‐layered insights from scRNA‐seq in rheumatic diseases. The outer layer highlights key cell subsets identified by scRNA‐seq in rheumatoid arthritis, systemic lupus erythematosus ...
Xinzhe Feng, Zhou Ji, Changhao Han, Zhi Li, Chenxu Liu, Weidong Xu   +5 more
wiley   +1 more source

Contribution of major histocompatibility complex class II immunostaining in distinguishing idiopathic inflammatory myopathy subgroups: A histopathological cohort study. [PDF]

J Neuropathol Exp Neurol
Lessard LER, Robert M, Fenouil T, Mounier R, Landel V, Carlesimo M, Hot A, Chazaud B, Laumonier T, Streichenberger N, Gallay L.   +10 more
europepmc   +1 more source

Major histocompatibility complex and coronary artery disease: Special emphasis on Chlamydia pneumoniae, and periodontitis

, 2008
Anil Palikhe
openalex   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Graft survival of major histocompatibility complex deficient stem cell-derived retinal cells. [PDF]

Commun Med (Lond)
Ishida M, Masuda T, Sakai N, Nakai-Futatsugi Y, Kamao H, Shiina T, Takahashi M, Sugita S.   +7 more
europepmc   +1 more source

Regulatory T Cells and Nanomaterials: Dual Perspectives in Therapeutics and Immunomodulation

Small Science, EarlyView.
Tregs control immune tolerance but can also enable tumor escape. Nanomaterials can now expand or stabilize Tregs to treat autoimmunity and support transplantation or conversely disrupt tumor Tregs to boost antitumor immunity. We also discuss unintended Treg modulation by nanoparticles, safety and manufacturing challenges, and future translational ...
Yiyin Chen, Haibo Huang, Xiang Wang, Xinghao Yu, Ziyan Huang, Zhou Jin, Chen Chen, Yan Chen, Bruce R. Blazar, Yang Xu, Yunjie Lu   +10 more
wiley   +1 more source

Atom-level mechanism of tapasin-independent peptide editing by Major Histocompatibility Complex class I molecules

Turner S, Darley R, Essex JW, Sim MJW, van Hateren A, Elliott T.   +5 more
europepmc   +1 more source

Europeans and Americans of European origin show differences between their biological pathways related to the major histocompatibility complex. [PDF]

Sci Rep
Vaulin A, Karpulevich E, Kasianov A, Morozova I.   +3 more
europepmc   +1 more source

Lymph Node‐Targeted Nanomaterials for Controlled Nano‐Immunotherapy

Small Structures, EarlyView.
This study primarily investigates lymph node‐targeted immunotherapeutic strategies, focusing on the mechanisms of immune response regulation within lymph nodes. By targeting distinct immune signaling pathways, we systematically explore the development of nanodrug delivery systems specifically designed for lymph node targeting to achieve enhanced ...
Yitong Zhao, Mengjun Wang, Ming Ma, Yu Zhang, Haoan Wu   +4 more
wiley   +1 more source

Development of a Stable Peptide-Major Histocompatibility Complex (MHC) via Sortase and Click Chemistry. [PDF]

ACS Pharmacol Transl Sci
Uslu SC, Lee UJ, Tavakolpour S, Abousaway O, Nili A, Bass L, Purwar P, Lacson E, Berland L, Kuhnast A, Clark LM, Picard D, Rakhshandehroo T, Mantri SR, Moravej H, Rashidian M.   +15 more
europepmc   +1 more source