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iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I. [PDF]

open access: yesCell Mol Life Sci
Calligaris M   +14 more
europepmc   +1 more source

Evolutionary aspects of allorecognition [PDF]

open access: yes, 2015
Ballarin, Loriano   +3 more
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COMPLEXITY IN THE MAJOR HISTOCOMPATIBILITY COMPLEX

International Journal of Immunogenetics, 1992
SUMMARYThe human major histocompatibility complex (MHC) is one of the most intensively studied regions of the human genome, containing over 70 known genes and spanning about 4 million base pairs (4Mbp) of DNA on chromosome 6p21.3 (Klein, 1986). It can be divided up into three regions: the class I region (telomeric), the class II region (centromeric ...
J. Trowsdale, R. D. Campbell
openaire   +3 more sources

The Major Histocompatibility Complex

Clinical Immunology Newsletter, 1986
At the beginning of this century, Tyzzer and Loeb showed that tumors of a strain of mice (A/A) grow normally if they are transplanted into mice of the same inbred strain (syngeneic, see Table 6.1); however, they are rejected by mice of another inbred strain (allogeneic, e.g., B/B).
Reinhard Burger, Dietrich Götze
openaire   +4 more sources

The major histocompatibility complex origin

Immunological Reviews, 2004
Summary:  The present review focuses on the history of genes involved in the major histocompatibility complex (MHC), with a special emphasis on class I function in peptide presentation. The MHC class II story is covered in less detail, as it does not have a major impact on the general understanding of the MHC evolution. We first redefine the MHC as the
Danchin, Etienne   +6 more
openaire   +4 more sources

The major histocompatibility complex in swine

Immunological Reviews, 1999
Summary: In swine, the major histocompatibility complex (Mhc) or swine leukocyte antigen (SLA) is located on chromosome 7 and divided by the centromere. Thus, the telomeric class I and more centromeric class III regions are located on the p arm and the class II region is located on the q arm.
Chardon, Patrick   +2 more
openaire   +4 more sources

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