Results 291 to 300 of about 242,210 (352)
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COMPLEXITY IN THE MAJOR HISTOCOMPATIBILITY COMPLEX
International Journal of Immunogenetics, 1992SUMMARYThe human major histocompatibility complex (MHC) is one of the most intensively studied regions of the human genome, containing over 70 known genes and spanning about 4 million base pairs (4Mbp) of DNA on chromosome 6p21.3 (Klein, 1986). It can be divided up into three regions: the class I region (telomeric), the class II region (centromeric ...
J, Trowsdale, R D, Campbell
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The major histocompatibility complex in the chicken
Trends in Genetics, 1989The chicken B complex is the first non-mammalian MHC characterized at the molecular level. It differs from the human HLA and murine H-2 complexes in the small size of the class I (B-F) and class II (B-L) genes and their close proximity. This proximity accounts for the absence of recombination between B-F and B-L genes and leaves no space for class III ...
Guillemot, F +3 more
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The Major Histocompatibility Complex and Inflammation
Southern Medical Journal, 2000The major histocompatibility complex (MHC) is of major medical interest because of its contribution to transplant rejection and to variation among individuals in susceptibility to a variety of autoimmune disorders. In addition to its role in influencing the propensity for known autoimmune diseases, the MHC contains genes contributing to several other ...
A, Blum, H, Miller
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The major histocompatibility complex origin
Immunological Reviews, 2004Summary: The present review focuses on the history of genes involved in the major histocompatibility complex (MHC), with a special emphasis on class I function in peptide presentation. The MHC class II story is covered in less detail, as it does not have a major impact on the general understanding of the MHC evolution. We first redefine the MHC as the
Danchin, Etienne +6 more
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The Major Histocompatibility Complex of Frogs
Immunological Reviews, 1990Article synthese sur la relation entre l'expression des antigenes du complexe majeur d'histocompatibilite et de developpement des precurseurs de lymphocytes T chez les ...
M F, Flajnik, L, Du Pasquier
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Birth of the Major Histocompatibility Complex
Scandinavian Journal of Immunology, 1998Klein J, Sato A. Birth of the Major Histocompatibility Complex.
J, Klein, A, Sato
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The major histocompatibility complex of primates
Genetica, 1987The major histocompatibility complex (MHC) encodes cell surface glycoproteins that function in self-nonself recognition and in allograft rejection. Among primates, the MHC has been well defined only in the human; in the chimpanzee and in two species of macaque monkeys the MHC is less well characterized.
E R, Heise +6 more
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The major histocompatibility complex in swine
Immunological Reviews, 1999Summary: In swine, the major histocompatibility complex (Mhc) or swine leukocyte antigen (SLA) is located on chromosome 7 and divided by the centromere. Thus, the telomeric class I and more centromeric class III regions are located on the p arm and the class II region is located on the q arm.
Chardon, Patrick +2 more
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