Results 71 to 80 of about 291 (249)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

MULTIPLICATIVE CHAOS AND DIMENSION OF A MEASURE

Let $ X= {X_k(ω,t)}_{t in T} $, $ k in N $, be an independent sequence of Gaussian processes with mean 0 on a locally compact separable metric space $ (T,d) $, and assume that the covariance functions are non-negative and $ sum _k[X_k( omega ,s) X_k ...
Tamashiro, Masakazu, 玉城, 政和
core   +1 more source

The difference of human gut microbiome in colorectal cancer with and without metastases. [PDF]

Front Oncol, 2022
Sun L, Zhu Z, Jia X, Ying X, Wang B, Wang P, Zhang S, Yu J.   +7 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The genomic sequence and analysis of the swine major histocompatibility complex

Genomics, 2006
We describe the generation and analysis of an integrated sequence map of a 2.4-Mb region of pig chromosome 7, comprising the classical class I region, the extended and classical class II regions, and the class III region of the major histocompatibility complex (MHC), also known as swine leukocyte antigen (SLA) complex.
Renard, Christine, Hart, E., Sehra, H., Beasley, H., Coggil, P., Howe, K., Harrow, J., Gilbert, Jean-Charles, Sims, S., Rogers, J., Ando, A., Shinegari, A., Shiina, T., Inoko, H., Chardon, Patrick, Beck, S.   +15 more
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

MULTIPLICATIVE CHAOS AND DIMENSION OF A MEASURE

, 1994
Let $ X= {X_k(ω,t)}_{t in T} $, $ k in N $, be an independent sequence of Gaussian processes with mean 0 on a locally compact separable metric space $ (T,d) $, and assume that the covariance functions are non-negative and $ sum _k[X_k( omega ,s) X_k ...
Tamashiro, Masakazu, 玉城, 政和
core  

A proximal distance algorithm for likelihood-based sparse covariance estimation. [PDF]

Biometrika, 2022
Xu J, Lange K.
europepmc   +1 more source