Results 51 to 60 of about 1,922 (249)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Uniform Central Limit Theorem for martingales [PDF]

, 2014
We study some sufficient conditions imposed on the sequence of martingale differences (m.d.) in the separable Banach spaces of continuous functions defined on the metric compact set for the Central Limit Theorem in this space.
Sirota, L.
core  

Discrepancy, chaining and subgaussian processes

, 2011
We show that for a typical coordinate projection of a subgaussian class of functions, the infimum over signs $\inf_{(\epsilon_i)}{\sup_{f\in F}}|{\sum_{i=1}^k\epsilon_i}f(X_i)|$ is asymptotically smaller than the expectation over signs as a function of ...
Mendelson, Shahar
core   +1 more source

Sequence Analysis of Goat Major Histocompatibility Complex Class I Genes [PDF]

Journal of Dairy Science, 2008
The polymorphism of major histocompatibility complex (MHC) class I genes has been often involved in the resistance/susceptibility to a variety of infectious and parasitic diseases. In this work, the complete sequence of the coding region of a major histocompatibility complex (MHC) class I gene in goats (Cahi-N*01701, GenBank accession no.
Zidi, Ali, Sànchez, A., Obexer-Ruf, Gabriela, Amills, Marcel   +3 more
openaire   +3 more sources

Newton's method and regularly smooth operators

Journal of Numerical Analysis and Approximation Theory, 2011
A semilocal convergence analysis for Newton's method in a Banach space setting is provided in this study. Using a combination of regularly smooth and center regularly smooth conditions on the operator involved, we obtain more precise majorizing sequences
Ioannis K. Argyros
doaj   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Consistency properties of a simulation-based estimator for dynamic processes

, 2010
This paper considers a simulation-based estimator for a general class of Markovian processes and explores some strong consistency properties of the estimator.
Santos, Manuel S.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A simple tool for bounding the deviation of random matrices on geometric sets

, 2016
Let $A$ be an isotropic, sub-gaussian $m \times n$ matrix. We prove that the process $Z_x := \|Ax\|_2 - \sqrt m \|x\|_2$ has sub-gaussian increments.
Liaw, Christopher, Mehrabian, Abbas, Plan, Yaniv, Vershynin, Roman   +3 more
core   +1 more source

Genome sequencing identifies major causes of severe intellectual disability

Nature, 2014
Severe intellectual disability (ID) occurs in 0.5% of newborns and is thought to be largely genetic in origin. The extensive genetic heterogeneity of this disorder requires a genome-wide detection of all types of genetic variation. Microarray studies and, more recently, exome sequencing have demonstrated the importance of de novo copy number variations
Gilissen, C., Hehir-Kwa, J.Y., Thung, D.T., van de Vorst, M., van Bon, B.W.M., Willemsen, M.H., Willemsen, M.H., Kwint, M., Janssen, I.M., Hoischen, A., Schenck, A., Leach, R., Klein, R., Tearle, R., Bo, T., Pfundt, R., Yntema, H.G., de Vries, L.B.A., Kleefstra, T., Brunner, H.G., Vissers, L.E.L.M., Veltman, J.A.   +21 more
openaire   +5 more sources