Results 31 to 40 of about 291 (249)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Convergence analysis for the two-step Newton method of order four

open access: yesJournal of Numerical Analysis and Approximation Theory, 2014
We provide a tighter than before convergence analysis for the two-step Newton method of order four using recurrent functions. Numerical examples are also provided in this study.
Ioannis K. Argyros, Sanjay K. Khattri
doaj   +2 more sources

Global majority consensus by local majority polling on graphs of a given degree sequence

open access: yesDiscrete Applied Mathematics, 2015
Suppose in a graph $G$ vertices can be either red or blue. Let $k$ be odd. At each time step, each vertex $v$ in $G$ polls $k$ random neighbours and takes the majority colour. If it doesn't have $k$ neighbours, it simply polls all of them, or all less one if the degree of $v$ is even.
Mohammed Amin Abdullah 0001, Moez Draief
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An improved semilocal convergence analysis for the midpoint method

open access: yesJournal of Numerical Analysis and Approximation Theory, 2016
We expand the applicability of the midpoint method for approximating a locally unique solution of nonlinear equations in a Banach space setting. Our majorizing sequences are finer than the known results in scientific literature [1,3,4,5,6,7,8,9,10,11,19,
Ioannis K. Argyros, Sanjay K. Khattri
doaj   +2 more sources

The Papillomavirus Episteme: a major update to the papillomavirus sequence database [PDF]

open access: yesNucleic Acids Research, 2016
The Papillomavirus Episteme (PaVE) is a database of curated papillomavirus genomic sequences, accompanied by web-based sequence analysis tools. This update describes the addition of major new features. The papillomavirus genomes within PaVE have been further annotated, and now includes the major spliced mRNA transcripts. Viral genes and transcripts can
Koenraad Van Doorslaer   +9 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The polytope of degree sequences

open access: yes, 1989
A nonnegative integer sequence (d1,d2,…,dn) is called a degree sequence if there exists a simple graph on the vertex set V= {1,2,…,n} such that deg(i)= di for all i. The degree sequence of a threshold graph is a threshold sequence.
Srinivasan, Murali K., Peled, Uri N.
core   +1 more source

Extended Parametric Family of Two-Step Methods with Applications for Solving Nonlinear Equations or Systems

open access: yesAxioms
The parametric family of two-step methods, with its special cases, has been introduced in various papers. However, in most cases, the local convergence analysis relies on the existence of derivatives of orders that the method does not require.
Ioannis K. Argyros   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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