Results 91 to 100 of about 2,467,727 (306)

Why Do People Adopt, or Reject, Smartphone Password Managers? [PDF]

, 2016
People use weak passwords for a variety of reasons, the most prescient of these being memory load and inconvenience. The motivation to choose weak passwords is even more compelling on Smartphones because entering complex passwords is particularly time ...
Alkaldi, Nora, Renaud, Karen
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

An alternative approach to a complex issue: Youth-designed strategies for the prevention of teenage pregnancy in schools

Perspectives in Education, 2018
Teenage pregnancy of school-going girls is a persistent concern, not only in South Africa, but globally. Despite various curricular responses aimed at educating young people about prevention, the numbers continue to rise.
F. Hendricks, L. Wood
doaj   +3 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Avaliação do Brincar de Faz de Conta de Pré-Escolares: Revisão Integrativa da Literatura

Revista Brasileira de Educação Especial
RESUMO: esta revisão integrativa da literatura objetivou identificar estudos sobre como o brincar simbólico/faz de conta de pré-escolares tem sido avaliado, quais os objetivos destes estudos e quais instrumentos têm sido utilizados para avaliar esse ...
Renata Valdívia LUCISANO, Letícia De Carli NOVAES, Amanda Mota Pacciulio SPOSITO, Luzia Iara PFEIFER   +3 more
doaj   +1 more source

The Technology Innovation Program [PDF]

, 2008
[Excerpt] The Technology Innovation Program (TIP) at the National Institute of Standards and Technology (NIST) was established in 2007 to replace the Advanced Technology Program (ATP).
Schact, Wendy H
core   +10 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Mining and prioritization of association rules for big data: multi-criteria decision analysis approach

Journal of Big Data, 2017
Data mining techniques and extracting patterns from large datasets play a vital role in knowledge discovery. Most of the decision makers encounter a large number of decision rules resulted from association rules mining.
Addi Ait-Mlouk, Tarik Agouti, Fatima Gharnati   +2 more
doaj   +1 more source

Needs Met Through Role-Playing Games: A Fantasy Theme Analysis of Dungeons & Dragons [PDF]

, 2013
Dungeons & Dragons (D&D) is an immersive fantasy role-playing game (RPG) which allows players to fulfill real-world social needs through interaction.
Adams, Aubrie S.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source