Results 111 to 120 of about 4,376,499 (301)

What are the Latest Trends in Career Pathing Models as Well as the Most Effective Ways to Accelerate High Potential Development? [PDF]

open access: yes, 2014
The war for talent is raging, making attracting, retaining, and developing high-performers more challenging than ever. Many of the “Baby Boomer” executives will be retiring in the near future, and only 15% of organizations in North America and Asia ...
Li, Lin, Masannat, Jonathan, Yang, Jing
core   +1 more source

Engineering multiferroism in CaMnO$_3$

open access: yes, 2008
From first-principles calculations, we investigate the structural instabilities of CaMnO$_3$. We point out that, on top of a strong antiferrodistortive instability responsible for its orthorhombic ground-state, the cubic perovskite structure of CaMnO$_3$
Eric Bousquet   +3 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Make/Believe: UK design for performance 2011 – 2015 [PDF]

open access: yes
Curator of selected UK work at the Prague Quadrennial, Prague, Czech Republic, 17 – 28 June ...
Burnett, K
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Swami Vivekananda's ethics of religion : a contribution to a modern concept of religion and inter-religious relations [PDF]

open access: yes, 1997
Many religious people believe that the integration of world society is of the greatest importance for mankind. They think that the religions of the world should strive to attain this goal through multi-religious agreement, through inter-religious ...
Weber, Edmund
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Hidden Connection in City-wide Reform: How Charter Schools Can Bring Equity to Public Education [PDF]

open access: yes, 2015
Many civic leaders believe that the New Orleans reform strategy holds promise for increasing educational outcomes in other cities. This is likely true. But this is also true: New Orleans continues to make an equally meaningful contribution to advancing ...
Neerav Kingsland
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

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