Results 11 to 20 of about 553,537 (177)

Manilkara zapota (L.) P. Royen Leaf Mitigates Colitis-Associated Colon Cancer through Anti-inflammatory Modulation in BALB/C Mice. [PDF]

Adv Pharmacol Pharm Sci
Colitis‐associated colon cancer (CAC) arises from prolonged inflammation of the inner colon lining. An alternative approach to treating or preventing CAC involves the use of natural products such as Manilkara zapota (L.) P. Royen or M. zapota, which has been studied for its medicinal and pharmacological properties.
Mohd Tamsir N, Mohd Esa N, Shafie NH, Hamzah H.   +3 more
europepmc   +2 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple-negative breast cancer. [PDF]

Mol Oncol
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Yusoh NA, Su L, Chia SL, Tian X, Ahmad H, Gill MR.   +5 more
europepmc   +2 more sources

Amide proton transfer imaging in stroke

NMR in Biomedicine, Volume 36, Issue 6, June 2023., 2023
Amide proton transfer (APT) imaging has shown promise in detecting ischemic tissue acidosis following impaired aerobic metabolism in animal models and in human stroke patients due to the sensitivity of the amide proton exchange rate to changes in pH within the physiological range.
Hye‐Young Heo, Yee Kai Tee, George Harston, Richard Leigh, Michael A. Chappell   +4 more
wiley   +1 more source

Busting the Breast Cancer with AstraZeneca’s Gefitinib

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2023, Issue 1, 2023., 2023
Breast cancer is the most common cancer diagnosed in women, and in 2020, there were 684, 996 deaths due to this disease. Epidermal growth factor receptors (EGFRs) and their respective ligands have been blamed for the pathogenesis and resistance to treatment in specific breast cancer cases.
S. Chemmalar, A. R. Intan Shameha, Che Azurahanim Che Abdullah, Nor Asma Ab Razak, Loqman Mohamad Yusof, Mokrish Ajat, Kim Wei Chan, Md Zuki Abu Bakar Zakaria, Srinivas Mutalik   +8 more
wiley   +1 more source

What's in a message: A systemic functional analysis of cancer prevention messages

International Journal of Applied Linguistics, Volume 32, Issue 1, Page 57-75, March 2022., 2022
Abstract This article provides some insights on how a particular reading from a theoretical framework can bring out details and problems with health communication posters. Using Michael Halliday's Systemic Functional Linguistics (SFL) framework, the article examines cancer prevention messages in cancer posters produced by the Ministry of Health ...
Collin Jerome, Su‐Hie Ting
wiley   +1 more source

In Vitro Growth Inhibition, Caspase‐Dependent Apoptosis, and S and G2/M Phase Arrest in Breast Cancer Cells Induced by Fluorine‐Incorporated Gold I Compound, Ph3PAu[SC(OMe)=NC6H4F‐3]

International Journal of Breast Cancer, Volume 2022, Issue 1, 2022., 2022
Gold‐based anticancer compounds have been attracting increasing research interest due to their ability to kill cancer cells resistant to platinum‐based compounds. Gold I‐ and gold III‐based complexes have shown satisfactory anticancer activities. In this study, two new fluorine‐incorporated gold (I) compounds such as Ph3PAu[SC(OMe)=NC6H4F‐3] and ...
Richard Ming Chuan Yu, Gayathri Thevi Selvarajah, Geok Chin Tan, Yoke-Kqueen Cheah, Arjun Singh   +4 more
wiley   +1 more source

Functional food mixtures: Inhibition of lipid peroxidation, HMGCoA reductase, and ACAT2 in hypercholesterolemia‐induced rats

Food Science &Nutrition, Volume 9, Issue 2, Page 875-887, February 2021., 2021
Mixtures of selected functional foods (MSFF) contained bioactive compounds (Monacolin K, naringin, tocopherol and glutamate) as anti‐hypercholesterolemic agents based on LC‐MS/MS analysis. Supplementation with MSFF were reduced the level of serum lipid profiles (TC and LDL), decreased serum liver profiles level (AST and ALT) in hypercholesterolemic ...
Noor Syafiqa Aqila Mohd Rosmi, Nurul Husna Shafie, Azrina Azlan, Maizaton Atmadini Abdullah   +3 more
wiley   +1 more source

Makna Peruntungan Usaha dalam Simbol di Budaya Imlek bagi Masyarakat Etnis Tionghoa Surabaya

Jurnal Psikologi Perseptual, 2020
Penggunaan warna merah dan kuning keemasan untuk perayaan Imlek Indonesia memang meriah. Perayaan ini sebagai momentum bagi masyarakat Tionghoa dalam melaksankan sembahyang pada leluhur dan berkumpul bersama keluarga.
Puspita Puji Rahayu, Priscilla Titis Indiarti   +1 more
doaj   +1 more source

Chemical Composition and Evaluation of the α‐Glucosidase Inhibitory and Cytotoxic Properties of Marine Algae Ulva intestinalis, Halimeda macroloba, and Sargassum ilicifolium

Evidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Seaweed has tremendous potentials as an alternative source of high‐quality food products that have attracted research in recent times, due to their abundance and diversity. In the present study, three selected seaweed species commonly found in the Malaysian Peninsular, Ulva intestinalis, Halimeda macroloba, and Sargassum ilicifolium, were subjected to ...
Muhammad Farhan Nazarudin, Azizul Isha, Siti Nurulhuda Mastuki, Nooraini Mohd. Ain, Natrah Fatin Mohd Ikhsan, Atifa Zainal Abidin, Mohammed Aliyu-Paiko, Miguel Vilas-Boas   +7 more
wiley   +1 more source

Equilibrative Nucleoside Transporter 2: Properties and Physiological Roles

BioMed Research International, Volume 2020, Issue 1, 2020., 2020
Equilibrative nucleoside transporter 2 (ENT2) is a bidirectional transporter embedded in the biological membrane and is ubiquitously found in most tissue and cell types. ENT2 mediates the uptake of purine and pyrimidine nucleosides and nucleobase besides transporting a variety of nucleoside‐derived drugs, mostly in anticancer therapy.
Safaa M. Naes, Sharaniza Ab-Rahim, Musalmah Mazlan, Amirah Abdul Rahman, Da Ming Zhang   +4 more
wiley   +1 more source