Results 171 to 180 of about 244,171 (199)

Inflammation and Routine Laboratory Associations in Imported Falciparum Malaria Assessed by Partial Correlation Analysis. [PDF]

Acta Parasitol
Pikor D, Cymerys M, Paul M.
europepmc   +1 more source

Key practices for ethical research during scientific expeditions

Conservation Science and Practice, EarlyView.
In many cases, expeditionary practices undermined local knowledge and expertise. This perspective advocates for a shift from parachute science towards a collaborative research approach. We reflect on and suggest best practices during scientific expeditions within research teams and in the team's interactions with different communities.
Nelsy Niño‐Rodríguez, Camila Gómez, Juliana Soto‐Patiño, Andrés M. Cuervo, Andrés Sierra‐Ricaurte, Natalia Pérez‐Amaya, Carlos Del Cairo, Carlos Daniel Cadena, Jessica Díaz‐Cárdenas, David Ocampo, Carolina Soto‐Vargas, Daniel J. Mennill, Natalia Ocampo‐Peñuela   +12 more
wiley   +1 more source

Combining statistical and dynamical modelling to guide the design of cluster randomised trials for malaria. [PDF]

BMJ Glob Health
Challenger JD, Biggs J, Skarp J, Cook J, Churcher TS.   +4 more
europepmc   +1 more source

The Role of Research Funders in Promoting Ethical International Health Research Collaborations

Developing World Bioethics, EarlyView.
ABSTRACT Background International health research collaborations (IHRCs) between High Income countries (HICs) and Low‐and Middle‐Income Countries (LMICs) are essential in global health research, yet ethical challenges including the inequitable sharing of rewards and burdens among the research actors remain insufficiently addressed.
George Kwasi Barimah, Charles F. Hayfron‐Benjamin, Bennett Allen, Kyle Ferguson, Amos Laar   +4 more
wiley   +1 more source

Malaria Vaccine Rollout in Nigeria: Current Status and Challenges. [PDF]

Am J Trop Med Hyg
Oyegbade SA, Adeboye SO, Oni GJ, Oyegbade AP, Oziohu JJ, Duyann ZY, Owoyemi OC.   +6 more
europepmc   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

The FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath, Subhoja Chakraborty, Sampa Biswas   +2 more
wiley   +1 more source

Spatial Analysis of Malaria in Bangladesh: Insights from Bayesian Disease Mapping Models. [PDF]

PLoS One
Mimi U, Karim MR, Begum S, Eme KA.
europepmc   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Dynamics modelling and control strategies of malaria transmission interruption by antimalarial-treated nets. [PDF]

Infect Dis Model
Qiao F, Li G.
europepmc   +1 more source

Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes

The FEBS Journal, EarlyView.
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli, Rupesh Balaji Jayachandran, Jack Whitehead, Cédric Leyrat, Annabel v. Clanner, Guido C Paesen, Max Renner   +6 more
wiley   +1 more source