Results 221 to 230 of about 471,764 (290)

Public awareness and education: key to the success of the malaria vaccine rollout in Sudan. [PDF]

BMJ Glob Health
Mohammed AAEA, Elagib HKE, Ibrahim MAA, Rafai MAA, Ali ODMH, Yaseen OYM.   +5 more
europepmc   +1 more source

Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi

Proceedings of the National Academy of Sciences of the United States of America, 2015
V. Gantz, N. Jasinskiene, Olga Tatarenkova, Aniko Fazekas, V. Macias, E. Bier, A. James   +6 more
semanticscholar   +1 more source

The Role of Research Funders in Promoting Ethical International Health Research Collaborations

Developing World Bioethics, EarlyView.
ABSTRACT Background International health research collaborations (IHRCs) between High Income countries (HICs) and Low‐and Middle‐Income Countries (LMICs) are essential in global health research, yet ethical challenges including the inequitable sharing of rewards and burdens among the research actors remain insufficiently addressed.
George Kwasi Barimah, Charles F. Hayfron‐Benjamin, Bennett Allen, Kyle Ferguson, Amos Laar   +4 more
wiley   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

Household and community-based approaches to malaria and cholera prevention: A narrative review with case studies from Uganda and Mozambique. [PDF]

PLoS Negl Trop Dis
Guido G, Totaro V, Lochoro P, Ictho J, Occa E, Chhaganlal K, Segala FV, Dall'Oglio G, Mechendura BF, Gomonda E, Putoto G, Penco F, Asaduzzaman M, Nicastri E, Farkas FB, Iatta R, Lakatos B, Ali RW, Saracino A, Di Gennaro F.   +19 more
europepmc   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

The FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath, Subhoja Chakraborty, Sampa Biswas   +2 more
wiley   +1 more source

Healthcare providers' knowledge, perceptions and practices of malaria control strategies in the Republic of Guinea: insights from a qualitative study. [PDF]

BMJ Glob Health
Diallo EM, Langlet A, Onyango LA, Kourouma M, Kambou BM, Diallo FB, Bufferne A, Petrova A, Deyra M, Gay C, Camara A, Gerbaud L.   +11 more
europepmc   +1 more source

On Racialized, Gendered, Precarious Work: Struggles of Community Health Workers During the National Health Insurance Pilot Program in the Tshwane District, South Africa

Gender, Work &Organization, EarlyView.
ABSTRACT The infrastructure of precarious work is racialized and gendered, affecting disenfranchised Black women who carry the burden of low paid caregiving within the healthcare system. In South Africa, Community Health Workers, predominantly Black women from marginalized communities, have been vital in providing primary healthcare services at home ...
Sivuyisiwe Wonci
wiley   +1 more source

Synthesis and Standardization of Outcomes in Severe Malaria Treatment Trials: Protocol for the Development of a Core Outcome Set (the COSSMaT Study).

JMIR Res Protoc
Asamoah GD, Love SB, Gibb DM, Maitland K, George EC.   +4 more
europepmc   +1 more source

Randomized controlled trial of intravenous dexamethasone to prevent relapse in the treatment of migraine in a pediatric emergency department

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to evaluate whether a single dose of intravenous dexamethasone, when added to standard abortive therapy, reduces relapse of migraine after emergency department (ED) discharge in children and adolescents. Background Migraine is a leading cause of headache presentations to the ED for children and adolescents.
Geneviève Tourigny‐Ruel, Benoit Bailey, Sabrina Jean‐Charles, Jocelyn Gravel   +3 more
wiley   +1 more source