Results 61 to 70 of about 75,219 (231)

Rare but relevant: Nitrous oxide and peripheral neurotoxicity, what do we know?

open access: yesAddiction, Volume 120, Issue 5, Page 1046-1050, May 2025.
Abstract Nitrous oxide (N2O), used medically as an anaesthetic, has gained popularity as a recreational drug, with rising prevalence particularly among young adults. While its reinforcing and addictive potential remains debated, N2O is proven to be neurotoxic, especially with prolonged, heavy use, which is often unexpected for users.
Tibor M. Brunt   +2 more
wiley   +1 more source

Celiac disease [PDF]

open access: yes, 2006
Celiac disease is a chronic intestinal disease caused by intolerance to gluten. It is characterized by immune-mediated enteropathy, associated with maldigestion and malabsorption of most nutrients and vitamins.
Caspary, Wolfgang F.   +1 more
core  

The use of iron after surgery: a systematic review and meta‐analysis

open access: yesAnaesthesia, EarlyView.
Summary Introduction Anaemia in patients having surgery is associated with worse postoperative outcomes. Management with intravenous iron is an attractive therapeutic option, however, pre‐operative intravenous iron administration is challenging. Evidence from interventional trials suggests that the greatest benefit is after hospital discharge.
Jayne Lim   +3 more
wiley   +1 more source

Review Article: Novel Enzyme Therapy Design for Gluten Peptide Digestion Through Exopeptidase Supplementation

open access: yesAlimentary Pharmacology &Therapeutics, Volume 61, Issue 7, Page 1123-1139, April 2025.
Exopeptidases are key for completing protein digestion, including proline‐rich peptides, and are mostly produced by enterocytes of the intestinal brush border membrane. In coeliac disease, chronic inflammation leads to reduced brush border exopeptidase activity, exacerbating peptide accumulation.
Erin R. Bonner   +3 more
wiley   +1 more source

Women's Health Disorders in a Coeliac Disease Population After Diagnosis—A Nationwide Cohort Analysis

open access: yesAlimentary Pharmacology &Therapeutics, Volume 61, Issue 10, Page 1603-1611, May 2025.
Women with coeliac disease appear to have higher frequencies of subsequent women's health disorders. Specific conditions vary based on patient age, and clinician awareness is important for longitudinal patient care. ABSTRACT Background There is a female predominance of diagnosed coeliac disease with sex‐related differences in clinical presentation ...
Rama Nanah   +9 more
wiley   +1 more source

Anthropometric indices in individuals infected with ascaris lumbericoids in Iran [PDF]

open access: yes, 2009
Context: Ascaris Lumbericoids infection is more common in children and teenagers and in areas with poor sanitation or crowded living conditions.
Najafi, M.   +5 more
core  

How I treat iron‐refractory iron deficiency anaemia—An expert opinion‐based treatment guidance for children and adults

open access: yesBritish Journal of Haematology, Volume 206, Issue 4, Page 1067-1076, April 2025.
In iron‐refractory iron deficiency anaemia, inappropriately elevated hepcidin levels impair enteral iron absorption and iron release from macrophages by interacting with ferroportin. Oral iron supplements (containing ~30 mg Fe2+ per 100 mg) are generally ineffective due to this hepcidin–ferroportin interaction although, in some cases, this can be ...
V. Hoving   +3 more
wiley   +1 more source

The Impact of Metformin on Plasma Prolactin Levels in Antipsychotics‐Treated Men With Hyperprolactinemia and Early‐Onset Androgenic Alopecia

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Metformin decreases elevated levels of pituitary hormones. Little is known about the association between the reproductive axis and hormonal effects of this drug. The purpose of our study was to investigate whether activity of the hypothalamic‐pituitary‐gonadal axis determines metformin action on prolactin levels in men with prolactin
Robert Krysiak   +4 more
wiley   +1 more source

The latest evidence and guidance in lifestyle and surgical interventions to achieve weight loss in people with overweight or obesity

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue S2, Page 20-34, April 2025.
ABSTRACT Background The prevalence of obesity and related co‐morbidities has reached epidemic proportions. Effective evidence‐based treatment approaches are therefore important. Lifestyle intervention remains the mainstay of the treatment strategy to manage obesity.
Iskandar Idris, Oluwaseun Anyiam
wiley   +1 more source

Real world evidence of insulin and biosimilar insulin therapy—Opportunities to improve adherence, outcomes and cost‐effectiveness

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Insulin has been discovered for more than a century; however, its benefits to people with diabetes are yet to be fully realized due to barriers related to access, quality of care and costs. Insulin therapy remains the cornerstone of diabetes management. The multicausality of diabetes and its subtypes calls for comprehensive phenotyping and use
Aimin Yang   +4 more
wiley   +1 more source

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