Results 11 to 20 of about 270,836 (221)

Deep learning hybrid model for analyzing and predicting the impact of imported malaria cases from Africa on the rise of Plasmodium falciparum in China before and during the COVID-19 pandemic.

PLoS ONE, 2023
BackgroundPlasmodium falciparum cases are rising in China due to the imported malaria cases from African countries. The main goal of this study is to examine the impact of imported malaria cases in African countries on the rise of P.
Eric Kamana, Jijun Zhao
doaj   +1 more source

The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

Nature, 2015
Since the year 2000, a concerted campaign against malaria has led to unprecedented levels of intervention coverage across sub-Saharan Africa. Understanding the effect of this control effort is vital to inform future control planning.
S. Bhatt, D. Weiss, E. Cameron, D. Bisanzio, B. Mappin, U. Dalrymple, K. Battle, C. Moyes, Andrew J. Henry, P. Eckhoff, E. Wenger, O. Briët, O. Briët, M. Penny, M. Penny, T. Smith, T. Smith, A. Bennett, J. Yukich, T. Eisele, J. Griffin, C. Fergus, Michael Lynch, F. Lindgren, Justin M. Cohen, C. Murray, Dave L. Smith, Simon Iain Hay, Simon Iain Hay, Simon Iain Hay, R. Cibulskis, P. Gething   +31 more
semanticscholar   +1 more source

Spatial and temporal distribution of falciparum malaria in China

Malaria Journal, 2009
Background Falciparum malaria is the most deadly among the four main types of human malaria. Although great success has been achieved since the launch of the National Malaria Control Programme in 1955, malaria remains a serious public health problem in ...
Lin Hualiang, Lu Liang, Tian Linwei, Zhou Shuisen, Wu Haixia, Bi Yan, Ho Suzanne C, Liu Qiyong   +7 more
doaj   +1 more source

Performance of “VIKIA Malaria Ag Pf/Pan” (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infections

Malaria Journal, 2012
Background Recently, IMACCESS® developed a new malaria test (VIKIA Malaria Ag Pf/Pan™), based on the detection of falciparum malaria (HRP-2) and non-falciparum malaria (aldolase).
Chou Monidarin, Kim Saorin, Khim Nimol, Chy Sophy, Sum Sarorn, Dourng Dany, Canier Lydie, Nguon Chea, Ménard Didier   +8 more
doaj   +1 more source

Epidemiology of Plasmodium malariae and Plasmodium ovale spp. in Kinshasa Province, Democratic Republic of Congo

Nature Communications, 2023
Reports suggest non-falciparum species are an underappreciated cause of malaria in sub-Saharan Africa but their epidemiology is ill-defined, particularly in highly malaria-endemic regions.
Rachel Sendor, Kristin Banek, Melchior M. Kashamuka, Nono Mvuama, Joseph A. Bala, Marthe Nkalani, Georges Kihuma, Joseph Atibu, Kyaw L. Thwai, W. Matthew Svec, Varun Goel, Tommy Nseka, Jessica T. Lin, Jeffrey A. Bailey, Michael Emch, Margaret Carrel, Jonathan J. Juliano, Antoinette Tshefu, Jonathan B. Parr   +18 more
doaj   +1 more source

QUINIDINE IN FALCIPARUM MALARIA

The Lancet, 1981
Fourteen patients with falciparum malaria were successfully treated with oral quinidine. Twelve of these patients were followed for 35 days without recrudescence. In six patients the infection had already recrudesced after antimalarial treatment, which in two cases had included a full course of quinine.
Nicholas J. White, Nicholas J. White, Tan Chongsuphajaisiddhi, Tan Chongsuphajaisiddhi, David A. Warrell, David A. Warrell, Danai Bunnag, Danai Bunnag, Sornchai Looareesuwan, Sornchai Looareesuwan, Harinasuta T, Harinasuta T   +11 more
openaire   +3 more sources

The treatment of severe falciparum malaria. [PDF]

BMJ, 1977
In severe falciparum malaria there is a pathophysiological cascade beginning with changes in the parasitized red blood cells which induce intermediate effects, in turn contributing to dysfunction of several organs. A low serum albumin is a common but often unrecognized finding which may contribute to oedema especially in the lung and brain.
W, Peters, A P, Hall
openaire   +5 more sources

IgM in human immunity to Plasmodium falciparum malaria

Science Advances, 2019
IgM is an important and long-lived component of anti-malarial immunity in humans and blocks infection of red blood cells. Most studies on human immunity to malaria have focused on the roles of immunoglobulin G (IgG), whereas the roles of IgM remain ...
Michelle J. Boyle, Michelle J. Boyle, Jo-Anne Chan, Irene Handayuni, L. Reiling, G. Feng, G. Feng, A. Hilton, Liriye Kurtovic, Liriye Kurtovic, D. Oyong, Kim A. Piera, Bridget E. Barber, T. William, Damon P. Eisen, Gabriela Minigo, Christine Langer, D. Drew, F. Rivera, F. Amante, Thomas N. Williams, Thomas N. Williams, Samson M. Kinyanjui, Samson M. Kinyanjui, Kevin Marsh, Kevin Marsh, Denise L. Doolan, C. Engwerda, F. Fowkes, F. Fowkes, F. Fowkes, M. Grigg, Ivo Mueller, Ivo Mueller, Ivo Mueller, James S. McCarthy, James S. McCarthy, N. Anstey, James G. Beeson, James G. Beeson, James G. Beeson   +40 more
semanticscholar   +1 more source

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria

Angewandte Chemie, EarlyView.
AZD0156, an ATM kinase inhibitor in clinical development, shows promising multistage antiplasmodial activity by targeting Plasmodium falciparum phosphatidylinositol 4‐kinase (PfPI4Kβ). With an improved specificity profile relative to other PfPI4Kβ inhibitors and moderate efficacy in a P.
John G. Woodland, Dina Coertzen, Kathryn J. Wicht, Virginia Franco Hidalgo, Charisse Flerida A. Pasaje, Luiz C. Godoy, Tarrick Qahash, Mmakwena M. Mmonwa, Godwin A. Dziwornu, Lynn Wambua, Sarah Harries, Constance M. Korkor, Mathew Njoroge, Liezl Krugmann, Dale Taylor, Meta Leshabane, Henrico Langeveld, Tayla Rabie, Janette Reader, Mariëtte van der Watt, Nelius Venter, Erica Erlank, Ayesha S. Aswat, Lizette L. Koekemoer, Tomas Yeo, Jin H. Jeon, David A. Fidock, Francisco Javier Gamo, Sergio Wittlin, Jacquin C. Niles, Manuel Llinas, Lauren B. Coulson, Lyn‐Marié Birkholtz, Kelly Chibale   +33 more
wiley   +2 more sources

Cytokine profiles among patients co-infected with Plasmodium falciparum malaria and soil borne helminths attending Kampala International University Teaching Hospital, in Uganda

Allergy, Asthma & Clinical Immunology, 2018
Background Malaria and helminths share the same geographical distribution in tropical Africa. Studies of the interaction of helminth and malaria co-infection in humans have been few and are mainly epidemiological, with little information on cellular ...
Richard Bwanika, Charles D. Kato, Johnson Welishe, Daniel C. Mwandah   +3 more
doaj   +1 more source