Results 131 to 140 of about 258,588 (271)

Targeting the apical domain of the transferrin receptor: Development of a new protein scaffold for cellular delivery

open access: yesProtein Science, Volume 34, Issue 12, December 2025.
Abstract Human transferrin receptor 1 (TfR) is essential for cellular iron homeostasis by internalizing the iron carrier proteins transferrin and ferritin. It is also an entry point for various pathogens, such as South American hemorrhagic fever caused by arenaviruses and the malaria parasite Plasmodium vivax, which utilize TfR to gain access to cells.
Anuthariq Alikkam Veetil   +5 more
wiley   +1 more source

Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile

open access: yesPLoS Neglected Tropical Diseases, 2017
Plasmodium vivax is the most widely distributed human malaria parasite and responsible for large amounts of disease and burden [1]. The presence of P. vivax in the bone marrow was first noticed in the late 19th century [2], and examinations of sternal ...
Bàrbara Baro   +15 more
semanticscholar   +1 more source

Advancing Organ‐on‐Chip Models With a Sacrificial Granular Hydrogel Strategy for Enhanced Permeability and Biomimicry

open access: yesSmall Methods, Volume 9, Issue 12, December 1, 2025.
A reversed granular hydrogel strategy creates highly porous 3D matrices within bone marrow (BM)‐on‐chip devices. Sacrificial alginate microgels generate interconnected microporosity that enhances nano/microparticle and cell mobilitymimicking pathogen agents—from the perfused vascular channel into the BM compartment, while preventing cell sedimentation ...
Hugo R Caires   +10 more
wiley   +1 more source

Discovery of Malaria Cases on Forest Workers In Public Health Center, Teluk Kepayang, Tanah Bumbu, South Kalimantan

open access: yesBIO Web of Conferences, 2020
Regency of Tanah Bumbu has an annual parasitic incidence rate (API) 0.82 and in 2016 the number of API decreased to 0.48. However, there are malaria cases that still occur in the 5 (five) locations of the workplace of the public health center with the ...
Rahayu Nita   +2 more
doaj   +1 more source

Susceptibility to Plasmodium vivax malaria associated with DARC (Duffy antigen) polymorphisms is influenced by the time of exposure to malaria

open access: yesScientific Reports, 2018
Malaria has provided a major selective pressure and has modulated the genetic diversity of the human genome. The variants of the Duffy Antigen/Receptor for Chemokines (DARC) gene have probably been selected by malaria parasites, particularly the FY*O ...
F. Kano   +10 more
semanticscholar   +1 more source

Detecting signatures of balancing selection to identify targets of anti-parasite immunity.

open access: yes, 2010
Parasite antigen genes might evolve under frequency-dependent immune selection. The distinctive patterns of polymorphism that result can be detected using population genetic methods that test for signatures of balancing selection, allowing genes encoding
Conway, David J, Weedall, Gareth D
core   +1 more source

An improved Plasmodium cynomolgi genome assembly reveals an unexpected methyltransferase gene expansion. [PDF]

open access: yes, 2017
Background: Plasmodium cynomolgi, a non-human primate malaria parasite species, has been an important model parasite since its discovery in 1907. Similarities in the biology of P.
Berriman, Matt   +7 more
core   +2 more sources

Epidemiological Characteristics of Re-emerging Vivax Malaria in the Republic of Korea (1993–2017)

open access: yesKorean Journal of Parasitology, 2018
Historically, Plasmodium vivax malaria has been one of the most highly endemic parasitic diseases in the Korean Peninsula. Until the 1970s, vivax malaria was rarely directly lethal and was controlled through the Korean Government Program administered by ...
Y. Bahk   +6 more
semanticscholar   +1 more source

Immunogenic Modulations Induced by Prospective Anti-Malarial Herbal Extracts in Murine Model [PDF]

open access: yes, 2010
Keeping in view the ever increasing problem of drug resistance and affordability of the antimalarial drugs by the poor mass, herbal medicines can become an important and alternative sustainable strategy for malaria treatment.
Chinmoy Karjee   +11 more
core   +1 more source

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