Results 161 to 170 of about 869,297 (419)

Indoor residual spraying for malaria control in sub-Saharan Africa 1997 to 2017: an adjusted retrospective analysis

open access: yesMalaria Journal, 2019
Indoor residual spraying (IRS) is a key tool for controlling and eliminating malaria by targeting vectors. To support the development of effective intervention strategies it is important to understand the impact of vector control tools on malaria ...
J. Tangena   +14 more
semanticscholar   +1 more source

Malaria parasite detection increases during pregnancy in wild chimpanzees [PDF]

open access: yes, 2014
Background: The diversity of malaria parasites (Plasmodium sp.) infecting chimpanzees (Pan troglodytes) and their close relatedness with those infecting humans is well documented. However, their biology is still largely unexplored and there is a need for
Boesch, Christophe   +6 more
core   +4 more sources

Chemical Protein Engineering: Backbone Cyclization Rescues Folding of a 183‐Residue Truncated Domain of Malaria Parasite Protein PfAMA1

open access: yesChemistry – A European Journal, Accepted Article.
The interaction between apical membrane antigen 1 (PfAMA1) and rhoptry neck protein 2 (PfRON2) is crucial for Plasmodium falciparum red blood cell invasion, making it a key target for anti‐malarial drug development strategies. Here, we report the chemical synthesis of PfAMA1 domain‐I (PfAMA1‐DI) in both linear and backbone‐circularized forms, employing
Jamsad Mannuthodikayil   +4 more
wiley   +1 more source

Automated haematology analysis to diagnose malaria [PDF]

open access: yes, 2010
© 2010 licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any
Campuzano-Zuluaga, Germán   +2 more
core   +4 more sources

Immunological and Toxicological Assessment of Triterpenoid Saponins Bearing Lewis‐X‐ and QS‐21‐Based Trisaccharides

open access: yesChemistry – A European Journal, Accepted Article.
The search for safer and more effective vaccine adjuvants has intensified in recent years, with triterpenoid saponins like QS‐21 and its analogues emerging as promising candidates. We report the synthesis of a novel QS‐21 analogue featuring betulinic acid as aglycone, a lupane‐type triterpenoid with low toxicity derived from white birch bark.
Oscar Javier Gamboa Marin   +9 more
wiley   +1 more source

COP27 Climate Change Conference: Urgent action needed for Africa and the world

open access: yes, 2023
Natural Sciences, Volume 3, Issue 1, January 2023.
Lukoye Atwoli   +20 more
wiley   +1 more source

Evaluation of cervical cancer screening strategies in women living with HIV in Thailand

open access: yes
Cancer Communications, EarlyView.
Patumrat Sripan   +10 more
wiley   +1 more source

A Novel Inhibitor against the Bromodomain Protein 1 of the Malaria Pathogen Plasmodium Falciparum

open access: yesChemMedChem, EarlyView.
This article presents the development of a first‐in‐class inhibitor targeting the bromodomain protein PfBDP1 in Plasmodium falciparum, the deadliest variant of the malaria‐causing Plasmodium parasites. Through structure‐based drug design, the inhibitor interactions were characterized via X‐ray crystallography and isothermal titration calorimetry ...
Marius Amann   +10 more
wiley   +1 more source

A hybrid effectiveness-implementation study protocol to assess the effectiveness and chemoprevention efficacy of implementing seasonal malaria chemoprevention in five districts in Karamoja region, Uganda [version 2; peer review: 1 approved, 2 approved with reservations]

open access: yesGates Open Research, 2023
Background The World Health Organization (WHO) recommends seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine (SPAQ) for children aged 3 to 59 months, living in areas where malaria transmission is highly seasonal ...
Craig Bonnington   +12 more
doaj  

Malaria [PDF]

open access: yesBMJ, 2011
Mirza, D. M., Hashim, M. J., Sheikh, A.
openaire   +3 more sources

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