Results 11 to 20 of about 976,240 (379)

Malaria

open access: yesThe Lancet, 2018
Following unsuccessful eradication attempts there was a resurgence of malaria towards the end of the 20th century. Renewed control efforts using a range of improved tools, such as long-lasting insecticide-treated bednets and artemisinin-based combination therapies, have more than halved the global burden of disease, but it remains high with 445 000 ...
Ashley, E, Pyae Phyo, A, Woodrow, C
semanticscholar   +6 more sources

Severe malaria

open access: yesMalaria Journal, 2022
Severe malaria is a medical emergency. It is a major cause of preventable childhood death in tropical countries. Severe malaria justifies considerable global investment in malaria control and elimination yet, increasingly, international agencies, funders
N. J. White
semanticscholar   +1 more source

The economic burden of malaria: a systematic review

open access: yesMalaria Journal, 2022
Background Quantifying disease costs is critical for policymakers to set priorities, allocate resources, select control and prevention strategies, and evaluate the cost-effectiveness of interventions. Although malaria carries a very large disease burden,
M. Andrade   +9 more
semanticscholar   +1 more source

Malaria chemoprevention and drug resistance: a review of the literature and policy implications

open access: yesMalaria Journal, 2022
Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-malarial drugs used for chemoprevention is perennially threatened by drug resistance.
C. Plowe
semanticscholar   +1 more source

Reflections on the 2021 World Malaria Report and the future of malaria control

open access: yesMalaria Journal, 2022
The World Malaria Report, released in December 2021, reflects the unique challenges currently facing the global malaria community. The report showed the devastating toll of malaria, with an estimated 627,000 people losing their lives to the disease in ...
April Monroe   +4 more
semanticscholar   +1 more source

The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

open access: yesNature, 2015
Since the year 2000, a concerted campaign against malaria has led to unprecedented levels of intervention coverage across sub-Saharan Africa. Understanding the effect of this control effort is vital to inform future control planning.
S. Bhatt   +31 more
semanticscholar   +1 more source

Malaria-filaria coinfection in mice makes malarial disease more severe unless filarial infection achieves patency [PDF]

open access: yes, 2005
Coinfections are common in natural populations, and the literature suggests that helminth coinfection readily affects how the immune system manages malaria.
Allen, Judith E   +3 more
core   +3 more sources

Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania

open access: yesNature Communications, 2019
Four genome-wide associated loci are currently known for malaria susceptibility. Here, the authors expand on earlier work by combining data from 11 malaria-endemic countries and additional population sequencing informing an African-enriched imputation ...
Malaria Genomic Epidemiology Network
doaj   +1 more source

Malaria Diagnosis and the Plasmodium Life Cycle: the BFO Perspective [PDF]

open access: yes, 2009
Definitive diagnosis of malaria requires the demonstration through laboratory tests of the presence within the patient of malaria parasites or their components.
Barry Smith, Werner Ceusters
core   +3 more sources

Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria [PDF]

open access: yes, 2014
Systemic inflammation and sequestration of parasitized erythrocytes are central processes in the pathophysiology of severe Plasmodium falciparum childhood malaria. However, it is still not understood why some children are more at risks to develop malaria
Afolabi, Nathaniel K.   +19 more
core   +3 more sources

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