Results 31 to 40 of about 664,566 (304)

Severe childhood malaria syndromes defined by plasma proteome profiles [PDF]

, 2012
BACKGROUND Cerebral malaria (CM) and severe malarial anemia (SMA) are the most serious life-threatening clinical syndromes of Plasmodium falciparum infection in childhood.
A Hodgetts, Adebola E. Orimadegun, AE Orimadegun, AK Rowe, AL Conroy, Barry K. Ely, Biobele J. Brown, C Wu, D Agranoff, Delmiro Fernandez-Reyes, Dimitrios Athanasakis, FE Lovegrove, Felix O. Akinbami, Florence Burté, Francesca Battaglia, Francis Akinkunmi, FX Wu, G Sandhu, J Amzat, J Bryce, K Marsh, Kevin KA. Tetteh, Kikelomo Osinusi, LK Erdman, MC Papadopoulos, Nathaniel K. Afolabi, Olayinka Kowobari, Olugbemiro Sodeinde, RT Pang, RW Snow, S Rojas-Galeano, Samuel Omokhodion, SI Hay, SI Hay, SJ Ceesay, Wasiu A. Ajetunmobi, Wuraola A. Shokunbi   +36 more
core   +6 more sources

Adherence to referral advice and its associated factors among community drug distributors and caregiver during SMC implementation in nine states

Malaria Journal
Background Malaria is a global public health problem that disproportionately affects under-five children in poor resource countries. Nigeria accounted for the highest burden of malaria in Western Africa.
Taiwo Ibinaiye, Ayodeji Balogun, Emmanuel Salifu, Benjamin Amao, Emmanuel Musa, Daniel Emeto, Samuel Ayoola, Usman Hussaini, Chibuzo Oguoma, Abdullahi Abdulrazak, Zechariah Maleeks, Olabisi Ogunmola, Olusola Oresanya, Kunle Rotimi   +13 more
doaj   +1 more source

A feasibility study to assess non-clinical community health workers’ capacity to use simplified protocols and tools to treat severe acute malnutrition in Niger state Nigeria

BMC Health Services Research, 2021
Background Severe acute malnutrition (SAM) is a major determinant of childhood mortality and morbidity. Although integrated community case management (iCCM) of childhood illnesses is a strategy for increasing access to life-saving treatment, malnutrition
Olatunde Adesoro, Olusola Oresanya, Helen Counihan, Prudence Hamade, Dare Eguavon, Chika Emebo, Bethany Marron, Naoko Kozuki, Amina Isah, Patrick Gimba, Chris Osa Isokpunwu, Kolawole Maxwell, James K. Tibenderana   +12 more
doaj   +1 more source

Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia [PDF]

, 2017
Hydroxyurea treatment is recommended for children with sickle cell anemia (SCA) living in high-resource malaria-free regions, but its safety and efficacy in malaria-endemic sub-Saharan Africa, where the greatest sickle-cell burden exists, remain unknown.
Hodges, James S., Hume, Heather A., John, Chandy C., Kasirye, Phillip, Lane, Adam, Latham, Teresa S., Ndugwa, Christopher M., Opoka, Robert O., Ware, Russell E.   +8 more
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Urban–rural differences in seasonal malaria chemoprevention coverage and characteristics of target populations in nine states of Nigeria: a comparative cross-sectional study

Malaria Journal
Background Differences between urban and rural contexts in terms of sociodemographic characteristics, geographical features and risk perceptions may lead to disparities in coverage and related outcomes of community-based preventive interventions, such as
Taiwo Ibinaiye, Kunle Rotimi, Ayodeji Balogun, Adaeze Aidenagbon, Chibuzo Oguoma, Kevin Baker, Olabisi Ogunmola, Olusola Oresanya, Christian Rassi, Chuks Nnaji   +9 more
doaj   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Impact of seasonal malaria chemoprevention: a plausibility evaluation of routine data from health facilities in three implementing states in Nigeria

Malaria Journal
Background Seasonal malaria chemoprevention (SMC) has been recommended by the World Health Organization since 2012 for eligible children in areas where malaria transmission is highly seasonal and intense. By 2024, SMC had been successfully implemented in
Ebenezer C. Ikechukwu, Ekechi Okereke, Olabisi Ogunmola, Jennifer Chukwumerije, Daniel Emeto, Emmanuel Salifu, Ayodeji Balogun, Chibuzo Oguoma, Emmanuel Shekarau, Nnenna Ogbulafor, Eoin Cassidy, Christian Rassi, Olusola Oresanya, Chukwudi A. Nnaji   +13 more
doaj   +1 more source

Prospective evaluation of artemether-lumefantrine for the treatment of non-falciparum and mixed-species malaria in Gabon [PDF]

, 2012
Background: The recommendation of artemisinin combination therapy (ACT) as first-line treatment for uncomplicated falciparum malaria is supported by a plethora of high quality clinical trials.
Adegnika, Ayola A., Basra, Arti, Bélard, Sabine, Capan, Mesküre, Diop, Daisy A., Joanny, Fanny, Kleine, Christian, Kremsner, Peter G., Kurth, Florian, Mombo-Ngoma, Ghyslain, Mordmüller, Benjamin, Ramharter, Michael, Würbel, Heike   +12 more
core   +1 more source

Malaria [PDF]

JAMA, 2022
Walter, Kristin, John, Chandy C.
openaire   +2 more sources